Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482915 | 0.97 | THRB (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL8482916 | 0.97 | THRB (0.50) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL8373529 | 0.93 | MEN1 (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10896260 | 0.93 | MEN1 (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL27271897 | 0.93 | MEN1 (0.41) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL30297390 | 0.92 | TSHR (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL5520469 | 0.92 | TSHR (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL5520472 | 0.92 | TSHR (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL10170027 | 0.92 | TSHR (0.48) | HTTMEN1THRBKMT2AMAPT | |
| SCHEMBL27512003 | 0.91 | LPAR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0612720-B1 | Process for producing 1,4-dicyano-2-butene | SUMITOMO CHEMICAL CO (JP) | 1997-01-08 | — | — | EP | disclosed |
| US-5463103-A | Reacting butene derivative with hydrogen cyanide in presence of catalyst prepared from cuprous halide, lower alkylamine hydrohalide and Lewis acid or basic acetate, carbonate or bicarbonate | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0612720-A1 | Process for producing 1,4-dicyano-2-butene | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-08-31 | — | — | EP | disclosed |