Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531672 | 0.87 | HSD17B10 (0.56) | HSD17B10KMT2AMAPK1NPSR1TDP1 | |
| SCHEMBL8744119 | 0.81 | HSD17B10 (0.60) | HSD17B10KMT2AMAPK1NPSR1GAA | |
| SCHEMBL11510698 | 0.78 | KMT2A (0.55) | HSD17B10KMT2AMAPK1NPSR1GAA | |
| SCHEMBL27637380 | 0.78 | KMT2A (0.55) | KMT2AMAPK1NPSR1GAAHTT | |
| SCHEMBL7115345 | 0.77 | KMT2A (0.54) | HSD17B10KMT2AMAPK1NPSR1GAA | |
| SCHEMBL5650758 | 0.77 | TSHR (0.61) | KMT2AHTTMAPTPOLBMEN1 | |
| SCHEMBL29990540 | 0.77 | TSHR (0.61) | KMT2AHTTMAPTPOLBMEN1 | |
| SCHEMBL222270 | 0.77 | TDP1 (0.67) | HSD17B10KMT2AMAPK1NPSR1GAA | |
| SCHEMBL2197879 | 0.75 | MAPK1 (0.64) | KMT2AMAPK1NPSR1GAAHTT | |
| SCHEMBL85918 | 0.75 | HSD17B10 (1.00) | HSD17B10KMT2ATDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751768-A1 | ANTI-VIRAL AND ANTI-CANCER AGENTS | RADOPATH LIMITED (GB) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995024897-A1 | ANTI-VIRAL AND ANTI-CANCER AGENTS | RADOPATH LIMITED (GB) | 1995-09-21 | — | — | WO | disclosed |