SCHEMBL8744193

SCHEMBL8744193

Nc1ccccc1-n1nnc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 1/20 0.64
ALDH1A1 P00352 3/20 0.50
RAB9A P51151 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
THPO P40225 1/20 0.50
CYP4Z1 Q86W10 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.46
SLC9A1 P19634 4/20 0.46
POLB P06746 2/20 0.46
MAPK1 P28482 1/20 0.46
ATM Q13315 1/20 0.46
KEAP1 Q14145 1/20 0.46
KDM4E B2RXH2 2/20 0.44
NPC1 O15118 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
TSHR P16473 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15673969 0.88 KCNMA1 (0.58) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4
SCHEMBL14253674 0.81 KCNMA1 (0.55) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4
SCHEMBL15109556 0.80 KCNMA1 (0.50) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4
SCHEMBL15445028 0.78 KCNMA1 (0.55) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4
SCHEMBL10182849 0.78 KCNMA1 (0.51) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4
SCHEMBL23840194 0.78 KCNMA1 (0.64) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4
SCHEMBL80393 0.78 KCNMA1 (1.00) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4
SCHEMBL4209963 0.78 KCNMA1 (0.64) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4
SCHEMBL16491892 0.78 KCNMA1 (0.64) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4
SCHEMBL25862494 0.78 KCNMA1 (0.64) KCNMA1ALDH1A1RAB9ACYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2046279-B1 Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of uv radiation and cosmetic compositions thereof BASF SE (DE) 2014-05-14 EP disclosed
EP-2046279-B1 Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of uv radiation and cosmetic compositions thereof BASF SE (DE) 2014-05-14 EP disclosed
CN-101489525-B Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of UV radiation and cosmetic compositions thereof CIBA HOLDING INC 2013-06-19 CN disclosed
US-8221729-B2 Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of UV radiation and cosmetic compositions thereof BASF SE (DE) 2012-07-17 US disclosed
CN-101489525-A Use of aminophenylbenzotriazole derivatives for protecting human and animal skin and hair from the harmful effects of UV radiation and cosmetic compositions thereof CIBA HOLDING INC (CH) 2009-07-22 CN disclosed
EP-0630954-B1 Low-molecular-weight and polymeric liquid cristalline benztriazoles and their use BASF AG (DE) 1997-01-08 EP disclosed
US-5429770-A Photoconductors, electrography, fluorescent dyes BASF AKTIENGESELLSCHAFT (DE) 1995-07-04 US disclosed
EP-0630954-A1 Low-molecular-weight and polymeric liquid cristalline benztriazoles and their use BASF Aktiengesellschaft (DE) 1994-12-28 EP disclosed
US-5043435-A Fiber-reactive benzotriazolyl-phenyl diazonium compounds suitable as diazo compounds for the preparation of azo dyes, and process for preparing them HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-27 US disclosed
US-4946947-A Water-soluble azo compounds containing a benzotiazol-1-yl phenyl moiety as a diazo component which carry a fiber-reactive group of the vinylsulfone series SPRINGER HARTMUT (DE) 1990-08-07 US disclosed
US-4686285-A DYEING POLYMERS, NATURAL FIBERS, LEATHER OR PAPER SANDOZ LTD. (CH) 1987-08-11 US disclosed
US-4533612-A 2-SUBSTITUTED BENZOTRIAZOLES BASF AKTIENGESELLSCHAFT (DE) 1985-08-06 US disclosed