Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL8829513 | 0.89 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL3180 | 0.89 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL9557413 | 0.89 | TSHR (0.60) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL8159679 | 0.89 | TSHR (0.60) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL673371 | 0.87 | TSHR (0.50) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL31612430 | 0.86 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL23607549 | 0.86 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL2482159 | 0.86 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL4653222 | 0.86 | TSHR (0.58) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL14957201 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5625050-A | Modified oligonucleotides and intermediates useful in nucleic acid therapeutics | AMGEN INC. (US) | 1997-04-29 | — | — | US | disclosed |
| EP-0753002-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1997-01-15 | — | — | EP | disclosed |
| WO-1995026972-A1 | MODIFIED OLIGONUCLEOTIDES AND INTERMEDIATES USEFUL IN NUCLEIC ACID THERAPEUTICS | AMGEN INC. (US) | 1995-10-12 | — | — | WO | disclosed |