Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Acrylic Acid Ethyl Ester. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL31612430 | 0.91 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL202495 | 0.89 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL5831496 | 0.89 | TSHR (0.56) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL8829513 | 0.89 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL9557413 | 0.89 | TSHR (0.60) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL3180 | 0.89 | — | — | |
| Acrylic Acid Ethyl Ester SCHEMBL8159679 | 0.89 | TSHR (0.60) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL4647153 | 0.88 | TSHR (0.41) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL8744229 | 0.87 | TSHR (0.50) | TSHRHPGDTHRBALDH1A1TP53 | |
| Acrylic Acid Ethyl Ester SCHEMBL4377433 | 0.86 | TSHR (0.54) | TSHRHPGDTHRBALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 272 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376472-A1 | METHODS FOR PRODUCING CROSSLINKABLE OLIGOMERS | NUPLEX RESINS B.V. (NL) | 2015-12-31 | — | — | US | claimed |
| US-20120142848-A1 | METHODS FOR PRODUCING CROSSLINKABLE OLIGOMERS | NUPLEX RESINS B.V. (NL) | 2012-06-07 | — | — | US | claimed |
| US-7829070-B2 | molar excess of anionic groups; acrylic acid or methacrylic acid; (meth)acrylates; free radically-polymerizable unsaturated amino monomer; water soluble; elastic and strong hairspray; coating material for a solid dosage form; adhesive | BASF SE (DE) | 2010-11-09 | — | — | US | claimed |
| US-20100080763-A1 | ACRYLIC-BASED COPOLYMER COMPOSITIONS FOR COSMETIC AND PERSONAL CARE | 3M INNOVATIVE PROPERTIES COMPANY | 2010-04-01 | — | — | US | claimed |
| EP-1784435-B1 | METHODS FOR PRODUCING CROSSLINKABLE OLIGOMERS | NUPLEX RESINS BV (NL) | 2009-11-11 | — | — | EP | claimed |
| EP-1694725-B1 | AMPHOLYTIC ANIONIC COPOLYMERS | BASF SE (DE) | 2009-09-02 | — | — | EP | claimed |
| US-20080274343-A1 | THICK SOLID SURFACE LAMINATE PRODUCT AND METHOD OF MAKING SAME | THE DILLER CORPORATION (US) | 2008-11-06 | — | — | US | claimed |
| US-20080114125-A1 | Methods for Producing Crosslinkable Oligomers | NUPLEX RESINS B.V. (NL) | 2008-05-15 | — | — | US | claimed |
| US-20070141013-A1 | Ampholytic anionic copolymers | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-21 | — | — | US | claimed |
| EP-1784435-A1 | METHODS FOR PRODUCING CROSSLINKABLE OLIGOMERS | Nuplex Resins B.V. (NL) | 2007-05-16 | — | — | EP | claimed |
| US-6432894-B1 | SHAMPOO MIXTURE | L'OREAL (FR) | 2002-08-13 | — | — | US | claimed |
| EP-1088542-B1 | Hair washing composition based on one detergent surfactant, one cationic galactomannan gum and one acrylic terpolymer | OREAL (FR) | 2002-07-10 | — | — | EP | claimed |
| US-6383993-B1 | DETERGENT SURFACTANT FOR WASHING HAIR | L'OREAL (FR) | 2002-05-07 | — | — | US | claimed |
| US-6383996-B1 | SHAMPOO FOR HAIR WITH ANTIDANDRUFF AGENT AND DERIVATIVE OF 1-HYDROXY-2-PYRIDONE | L'OREAL (FR) | 2002-05-07 | — | — | US | claimed |
| US-6383995-B1 | DETERGENT SURFACTANT FOR WASHING HAIR | L'OREAL (FR) | 2002-05-07 | — | — | US | claimed |
| US-6344502-B1 | ALKYD RESIN, AMINE-FUNCTIONAL MONOMER | THE SHERWIN-WILLIAMS COMPANY | 2002-02-05 | — | — | US | claimed |
| EP-0832159-A4 | AUTOMOTIVE COATINGS FROM NON-AQUEOUS DISPERSIONS | SHERWIN WILLIAMS CO (US) | 2000-04-12 | — | — | EP | claimed |
| EP-0832159-A1 | AUTOMOTIVE COATINGS FROM NON-AQUEOUS DISPERSIONS | THE SHERWIN-WILLIAMS COMPANY (US) | 1998-04-01 | — | — | EP | claimed |
| WO-1996040828-A1 | AUTOMOTIVE COATINGS FROM NON-AQUEOUS DISPERSIONS | THE SHERWIN-WILLIAMS COMPANY (US) | 1996-12-19 | — | — | WO | claimed |
| US-5516820-A | SUBSTRATE COATED WITH A MULTILAYER DECORATIVE AND/OR PROTECTIVE COATING | BABJAK JOHN R (US) | 1996-05-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070141013-A1 | Ampholytic anionic copolymers | ALPP, ABHD16A, LIPA | TSHR 3622/4885HPGD 2224/4885THRB 4546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.