SCHEMBL8744231

SCHEMBL8744231

O=C1c2ccccc2C(=O)c2c1ccc(CO)c2[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.61
CYP3A4 P08684 5/20 0.61
TSHR P16473 1/20 0.61
SMN1; SMN2 Q16637 5/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
HPGD P15428 2/20 0.55
MAPT P10636 6/20 0.46
LMNA P02545 4/20 0.46
MAPK1 P28482 4/20 0.46
ELANE P08246 2/20 0.46
MEN1 O00255 5/20 0.44
KMT2A Q03164 5/20 0.44
CYP2D6 P10635 3/20 0.44
CYP2C19 P33261 3/20 0.44
CYP1A2 P05177 2/20 0.44
APEX1 P27695 2/20 0.44
POLB P06746 2/20 0.44
CASP6 P55212 1/20 0.44
PTPRC P08575 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11318929 0.86 ALDH1A1 (0.68) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1
SCHEMBL9490419 0.82 ALDH1A1 (0.58) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1
SCHEMBL10355812 0.80 ALDH1A1 (0.67) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1
SCHEMBL9490907 0.79 ALDH1A1 (0.58) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1
SCHEMBL155146 0.78 ALDH1A1 (0.69) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1
SCHEMBL9192176 0.77 SMN1; SMN2 (0.72) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1
Nitric Acid SCHEMBL11884408 0.77 ALDH1A1 (0.63) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1
SCHEMBL10355745 0.76 ALDH1A1 (0.67) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1
SCHEMBL27987835 0.76 ALDH1A1 (0.67) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1
SCHEMBL3276062 0.76 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0155231-B2 Image-producing process CIBA GEIGY AG (CH) 1997-01-15 EP disclosed
US-5508141-A AQUEOUS ACIDIC PHOTORESIST EMULSION CONTAINING RESIN, POSITIVE-ACTING PHOTOACTIVE FUNCTIONALITY, ACID, OXIDIZING AGENT, SURFACTANT W. R. GRACE & CO.-CONN. (US) 1996-04-16 US disclosed
CN-1030739-C Method for selectively coating metal surface, method for forming circuit pattern from metal surface and photosensitive emulsion used therefor GRACE W R & CO (US) 1996-01-17 CN disclosed
EP-0468002-A4 AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES GRACE W R & CO (US) 1995-08-09 EP disclosed
US-5232815-A Corrosion resistance W. R. GRACE & CO.-CONN. (US) 1993-08-03 US disclosed
EP-0518453-A1 A method of making electrical circuit traces W.R. Grace & Co.-Conn. (US) 1992-12-16 EP disclosed
EP-0468002-A1 AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES W.R. GRACE & CO.-CONN. (US) 1992-01-29 EP disclosed
US-5064746-A RADIATION-SENSITIVE MIXTURE FOR PHOTOSENSITIVE COATING MATERIALS AND THE PRODUCTION OF RELIEF PATTERNS AND RELIEF IMAGES BASF AKTIENGESELLSCHAFT (DE) 1991-11-12 US disclosed
CN-1054836-A Automatic deposition emulsion and the method for the metal surface being carried out selective protection with this emulsion GRACE W R & CO (US) 1991-09-25 CN disclosed
WO-1991008840-A1 AUTODEPOSITION EMULSION FOR SELECTIVELY PROTECTING METALLIC SURFACES W.R. GRACE & CO.-CONN. (US) 1991-06-27 WO disclosed
US-4822866-A PLASMA RESISTANT PHOTORESISTS; REMOVABLE WITH WEAK ALKALINE SOLUTIONS BASF AKTIENGESELLSCHAFT (DE) 1989-04-18 US disclosed
US-4812542-A PHOTORESISTS, LIGHT-SENSITIVE COATINGS BASF AKTIENGESELLSCHAFT (DE) 1989-03-14 US disclosed
US-4808682-A BLEND WITH OLEFINICALLY UNSATURATED SILICON COMPOUND BASF AKTIENGESELLSCHAFT (DE) 1989-02-28 US disclosed
US-4632900-A Process for the production of images after electrodeposition of positive photoresist on electrically conductive surface CIBA-GEIGY CORPORATION (US) 1986-12-30 US disclosed
EP-0155231-A2 Image-producing process CIBA-GEIGY AG (CH) 1985-09-18 EP disclosed