SCHEMBL8744273

SCHEMBL8744273

CCOCCCCCCc1cc(N(C)C)ccc1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HPSE Q9Y251 2/20 0.41
PPARA Q07869 2/20 0.39
PPARG P37231 1/20 0.39
SLC16A3 O15427 3/20 0.36
HDAC1 Q13547 1/20 0.36
KAT8 Q9H7Z6 2/20 0.35
RARB P10826 3/20 0.35
RARA P10276 1/20 0.35
RARG P13631 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3305470 0.89 SLC16A3 (0.43) HPSEPPARAPPARGSLC16A3KAT8
SCHEMBL6247855 0.86 PPARA (0.51) HPSEPPARAPPARGKAT8RARB
SCHEMBL9517713 0.86 PPARA (0.51) HPSEPPARAPPARGKAT8RARB
SCHEMBL4889679 0.86 PPARA (0.51) HPSEPPARAPPARGKAT8RARB
SCHEMBL38613 0.86 PPARA (0.51) HPSEPPARAPPARGKAT8RARB
SCHEMBL480460 0.85 PPARA (0.49) HPSEPPARAPPARGKAT8RARB
SCHEMBL308244 0.84 RARB (0.45) HPSEPPARAPPARGRARBRARA
SCHEMBL7750610 0.84 PPARA (0.49) HPSEPPARAPPARGKAT8RARB
SCHEMBL4914947 0.83 GABRP (0.49) HPSEPPARAPPARGSLC16A3HDAC1
Ammonia Solution, Strong SCHEMBL10715754 0.83 RARB (0.44) HPSEPPARAPPARGRARBRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0579079-B1 Cosmetic preparation for treating light-induced skin ageing SARA LEE DE NV (NL) 1997-01-22 EP disclosed
EP-0579078-B1 Cosmetic sunscreen BAYER AG (DE) 1996-03-06 EP disclosed
EP-0579078-A1 Cosmetic sunscreen BAYER AG (DE) 1994-01-19 EP disclosed
EP-0579079-A1 Cosmetic preparation for treating light-induced skin ageing BAYER AG (DE) 1994-01-19 EP disclosed
EP-0343444-B1 COSMETIC COMPOSITION CONTAINING RETINYL PALMITATE BAYER AG (DE) 1992-01-08 EP disclosed
EP-0343444-A2 Cosmetic composition containing retinyl palmitate BAYER AG (DE) 1989-11-29 EP disclosed