Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.68 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.63 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.63 |
| ▸ | CTSL | P07711 | 6/20 | 0.63 |
| ▸ | CTSS | P25774 | 3/20 | 0.63 |
| ▸ | CTSB | P07858 | 3/20 | 0.62 |
| ▸ | MME | P08473 | 1/20 | 0.60 |
| ▸ | ECE1 | P42892 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744665 | 1.00 | CTSK (0.68) | CTSKCAPN1CAPN2CTSLCTSS | |
| Carbon Dioxide SCHEMBL2251297 | 0.97 | CTSK (0.64) | CTSKCAPN1CAPN2CTSLCTSS | |
| SCHEMBL2251235 | 0.97 | CTSK (0.64) | CTSKCAPN1CAPN2CTSLCTSS | |
| SCHEMBL2251230 | 0.97 | CTSK (0.64) | CTSKCAPN1CAPN2CTSLCTSS | |
| SCHEMBL5598102 | 0.93 | CTSK (0.78) | CTSKCAPN1CAPN2CTSLCTSS | |
| SCHEMBL5598105 | 0.93 | CTSK (0.78) | CTSKCAPN1CAPN2CTSLCTSS | |
| SCHEMBL8972543 | 0.92 | CTSK (0.67) | CTSKCAPN1CAPN2CTSLCTSS | |
| SCHEMBL7324017 | 0.92 | CTSK (0.67) | CTSKCAPN1CAPN2CTSLCTSS | |
| SCHEMBL7324011 | 0.92 | CTSK (0.67) | CTSKCAPN1CAPN2CTSLCTSS | |
| SCHEMBL2251162 | 0.91 | CTSK (0.58) | CTSKCAPN1CAPN2CTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578978-B1 | Dipeptide derivative and prophylactic or therapeutic agent for bone diseases containing same as active ingredient | SUNTORY LTD (JP) | 1997-01-15 | — | — | EP | disclosed |
| EP-0543310-B1 | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LTD (JP) | 1996-03-27 | — | — | EP | disclosed |
| US-5399743-A | Osteoporosis, hypercalcemia | SUNTORY LIMITED (JP) | 1995-03-21 | — | — | US | disclosed |
| US-5395824-A | Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same | SUNTORY LIMITED (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0578978-A1 | Dipeptide derivative and prophylactic or therapeutic agent for bone diseases containing same as active ingredient | SUNTORY LIMITED (JP) | 1994-01-19 | — | — | EP | disclosed |