SCHEMBL8744767

SCHEMBL8744767

NN(CCC(=O)O)CCC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 5/20 0.47
EGLN1 Q9GZT9 2/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
PHF8 Q9UPP1 3/20 0.43
KDM2A Q9Y2K7 3/20 0.43
KDM4E B2RXH2 2/20 0.43
KDM5C P41229 2/20 0.43
SLC22A6 Q4U2R8 1/20 0.42
TSHR P16473 3/20 0.41
GABRR1 P24046 2/20 0.41
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
THRB P10828 2/20 0.41
BLM P54132 2/20 0.41
KMT2A Q03164 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
GABRR3 A8MPY1 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13494975 0.89 LMNA (0.46) LMNAEGLN1ALKBH5SUCNR1PHF8
SCHEMBL11429148 0.87 LMNA (0.44) LMNAEGLN1ALKBH5SUCNR1PHF8
SCHEMBL16153064 0.86 TDP1 (0.43) LMNAEGLN1ALKBH5SUCNR1PHF8
SCHEMBL2153538 0.84
SCHEMBL2806349 0.82 LMNA (0.53) LMNAEGLN1ALKBH5SUCNR1SLC22A6
SCHEMBL18127423 0.82 PHF8 (0.41) LMNAEGLN1ALKBH5SUCNR1PHF8
SCHEMBL22398276 0.81
SCHEMBL29955022 0.79
SCHEMBL29405740 0.77 LMNA (0.42) LMNAEGLN1ALKBH5SUCNR1PHF8
SCHEMBL163128 0.73 LMNA (0.53) LMNAEGLN1ALKBH5SUCNR1PHF8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024042008-A1 POLYMERIZABLE LIQUID CRYSTAL MATERIAL AND POLYMERIZED LIQUID CRYSTAL FILM MERCK PATENT GMBH (DE) 2024-02-29 WO disclosed
WO-2017008877-A1 COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS MERCK PATENT GMBH (DE) 2017-01-19 WO disclosed
EP-0353714-B1 Silver halide photographic photosensitive materials FUJI PHOTO FILM CO LTD (JP) 1997-01-22 EP disclosed