Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744686 | 0.84 | NPY5R (0.47) | KDM4EHPGDTSHRADORA1ADORA2A | |
| SCHEMBL8744702 | 0.84 | ERBB2 (0.49) | KDM4ELMNACYP2C19ADORA1ADORA2A | |
| SCHEMBL30918737 | 0.73 | MAPK14 (0.40) | LMNAPDE3BPDE3AMAPK14MAPK13 | |
| SCHEMBL7300360 | 0.73 | NPY5R (0.39) | LMNAPDE3BPDE3AMAPK14MAPK13 | |
| SCHEMBL28399047 | 0.72 | NPY5R (0.71) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL29330538 | 0.69 | LRRK2 (0.50) | KDM4EPDE5ALMNAHPGDTSHR | |
| SCHEMBL21773988 | 0.68 | ERBB2 (0.46) | KDM4ELMNACYP2C19ADORA1ADORA2A | |
| SCHEMBL8744781 | 0.66 | — | — | |
| SCHEMBL28402538 | 0.66 | MAPK13 (0.63) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL7374799 | 0.65 | SMPD3 (0.56) | KDM4ELMNAHPGDMAPK14MAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |