Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FLT1 | P17948 | 1/20 | 0.47 |
| ▸ | GRK5 | P34947 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.47 |
| ▸ | CDK8 | P49336 | 1/20 | 0.47 |
| ▸ | GSK3A | P49840 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PRKX | P51817 | 1/20 | 0.47 |
| ▸ | NEK2 | P51955 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.47 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.47 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744702 | 0.86 | ERBB2 (0.49) | NPY5RKDM4ESMN1; SMN2ADORA1ADORA2A | |
| SCHEMBL8744773 | 0.84 | KDM4E (0.44) | NPY5RCDK8GSK3BMAPK14HPGD | |
| SCHEMBL724250 | 0.77 | NPY5R (0.72) | NPY5RHPGDSMAPK14SMPD3HPGD | |
| SCHEMBL7601774 | 0.75 | HPGD (0.68) | NPY5RHPGDSSMPD3HPGDKDM4E | |
| SCHEMBL11601050 | 0.75 | HPGD (0.41) | NPY5RHPGDSCHEK1ABL1PDGFRB | |
| SCHEMBL31305589 | 0.74 | NPY5R (0.68) | NPY5RHPGDSMAPK14SMPD3HPGD | |
| SCHEMBL4083806 | 0.71 | PTGS1 (0.45) | NPY5RHPGDSSMPD3ADORA1MEN1 | |
| SCHEMBL7142762 | 0.71 | NPY5R (0.64) | NPY5RHPGDSMAPK14SMPD3HPGD | |
| SCHEMBL28399047 | 0.70 | NPY5R (0.71) | NPY5RHPGDSMAPK14SMPD3POLB | |
| SCHEMBL1690522 | 0.69 | ADORA3 (0.46) | NPY5RHPGDSMAPK14SMPD3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653421-B1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA (JP) | 1997-01-15 | — | — | EP | disclosed |
| US-5552557-A | Process for preparing 2-cyanoimidazole compounds by reaction of an amino ketone compound | ISHIHARA SANGYO KAISHA, LTD. (JP) | 1996-09-03 | — | — | US | disclosed |
| EP-0653421-A1 | Process for preparing 2-cyanoimidazole compounds | ISHIHARA SANGYO KAISHA LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |