SCHEMBL8744895

SCHEMBL8744895

COC(=O)N[C@H](C=O)C(C)OC

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
CTSK P43235 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9881515 1.00 TDP1 (0.35) TDP1CTSK
SCHEMBL18653179 1.00 TDP1 (0.35) TDP1CTSK
SCHEMBL12066443 1.00 TDP1 (0.35) TDP1CTSK
SCHEMBL23989898 0.83 CTSK (0.46) CTSK
SCHEMBL2519108 0.83 CTSK (0.46) CTSK
SCHEMBL881290 0.83 TDP1 (0.36) TDP1CTSK
SCHEMBL12462615 0.83 TDP1 (0.36) TDP1CTSK
SCHEMBL1994472 0.83 TDP1 (0.36) TDP1CTSK
SCHEMBL19650463 0.82 KMT2A (0.31)
SCHEMBL1991428 0.81 TDP1 (0.36) TDP1CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012068234-A2 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2012-05-24 WO disclosed
WO-2010132601-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. (US) 2010-11-18 WO disclosed