Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.70 |
| ▸ | HTR7 | P34969 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | DRD4 | P21917 | 4/20 | 0.61 |
| ▸ | DRD2 | P14416 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HRH2 | P25021 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9225440 | 0.87 | MAPK1 (0.81) | MAPK1HTR7DRD4DRD2DRD3 | |
| SCHEMBL9720681 | 0.84 | MAPK1 (0.78) | MAPK1HTR7DRD4DRD2DRD3 | |
| SCHEMBL8744984 | 0.83 | ATM (0.70) | HTR7DRD4DRD2KDM4ESMN1; SMN2 | |
| SCHEMBL6031726 | 0.83 | MAPK1 (0.80) | MAPK1HTR7DRD4DRD2DRD3 | |
| SCHEMBL6031061 | 0.83 | MAPK1 (0.80) | MAPK1HTR7DRD4DRD2DRD3 | |
| SCHEMBL18177886 | 0.83 | MAPK1 (1.00) | MAPK1HTR7DRD4DRD2DRD3 | |
| SCHEMBL19561754 | 0.83 | MAPK1 (0.80) | MAPK1HTR7DRD4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL8745009 | 0.82 | ATM (0.68) | HTR7DRD4DRD2KDM4ESMN1; SMN2 | |
| Bromide SCHEMBL6575673 | 0.82 | MAPK1 (0.78) | MAPK1HTR7DRD4DRD2DRD3 | |
| SCHEMBL8640886 | 0.81 | MAPK1 (0.69) | MAPK1HTR7DRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | claimed |
| EP-0753515-A2 | Benzylpiperazine derivatives as antiallergic and anti-inflammatory agents | Senju Pharmaceutical Co., Ltd. (JP) | 1997-01-15 | — | — | EP | disclosed |