Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 5/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19519203 | 1.00 | TSHR (0.47) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL8745030 | 1.00 | TSHR (0.47) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL6141331 | 1.00 | TSHR (0.47) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL15096837 | 1.00 | TSHR (0.47) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL8027738 | 1.00 | TSHR (0.47) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL7147818 | 1.00 | TSHR (0.47) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL766216 | 1.00 | TSHR (0.47) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL766010 | 1.00 | TSHR (0.47) | TSHRHTTTHRBMEN1KMT2A | |
| SCHEMBL1143522 | 0.98 | — | — | |
| SCHEMBL17738112 | 0.96 | HTT (0.54) | TSHRHTTTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0596197-B1 | Lubricating composition comprising an N-acyl-N-hydrocarbon- oxyalkyl aspartic acid compound | KING INDUSTRIES INC (US) | 1997-01-29 | — | — | EP | claimed |
| EP-0161626-B1 | SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL | FUJI PHOTO FILM CO., LTD. (JP) | 1990-12-05 | — | — | EP | claimed |
| US-5290960-A | Diacetylenic phospholipids containing heteroatom near diacetylenic functionality for modulation of microstructure morphology | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1994-03-01 | — | — | US | disclosed |
| US-4137329-A | Insecticidal propargyl ethers | HOFFMANN-LA ROCHE INC. (US) | 1979-01-30 | — | — | US | disclosed |