Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL793949 | 0.88 | SLC6A2 (0.44) | TSHRCASRCHRNB2CHRNA4SLC6A2 | |
| SCHEMBL22207673 | 0.84 | ALDH1A1 (0.41) | TSHRCASRCHRNB2CHRNA4SLC6A2 | |
| SCHEMBL7158465 | 0.79 | CASR (0.40) | CASRCYP2C19CYP1A2CYP2D6TRPA1 | |
| SCHEMBL7778374 | 0.73 | CASR (0.37) | TSHRCASRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13627603 | 0.73 | TSHR (0.52) | TSHRLTA4HCHRNB2CHRNA4SLC6A2 | |
| SCHEMBL16594620 | 0.73 | FFAR1 (0.35) | TSHRLTA4HCASRPPARGPPARA | |
| SCHEMBL6931929 | 0.72 | CASR (0.49) | TSHRCASRCYP2C19KMT2AMEN1 | |
| SCHEMBL1906076 | 0.72 | MEN1 (0.44) | CASRCYP2C19KMT2AMEN1CYP2D6 | |
| SCHEMBL20241505 | 0.72 | CASR (0.37) | TSHRCASRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11434362 | 0.72 | CASR (0.40) | TSHRCASRSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0466220-B1 | Carboxy containing monomers and polymers and latices prepared from same | JOHNSON & JOHNSON CLIN DIAG (US) | 1997-01-29 | — | — | EP | disclosed |
| US-5278267-A | Water insoluble vinyl aromatic polymer | EASTMAN KODAK COMPANY (US) | 1994-01-11 | — | — | US | disclosed |
| US-5210289-A | Homo or coploymers for medical diagnosis | EASTMAN KODAK COMPANY (US) | 1993-05-11 | — | — | US | disclosed |
| US-5149737-A | Carboxy group extended from polymer surface allows easier attachment of biological substances | EASTMAN KODAK COMPANY (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0466220-A2 | Carboxy containing monomers and polymers and latices prepared from same | Johnson & Johnson Clinical Diagnostics, Inc. (US) | 1992-01-15 | — | — | EP | disclosed |