SCHEMBL8745301

SCHEMBL8745301

CCOC(=O)CCCBr.COCCOC

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.53
ALDH1A1 P00352 3/20 0.50
TRPA1 O75762 1/20 0.50
DGKA P23743 1/20 0.44
NR1I2 O75469 1/20 0.43
PGR P06401 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
PTGS2 P35354 1/20 0.43
PDE4D Q08499 1/20 0.43
GAA P10253 2/20 0.43
MGAM O43451 1/20 0.43
SI P14410 1/20 0.43
MGAM2 Q2M2H8 1/20 0.43
RAB9A P51151 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TSHR P16473 3/20 0.41
ALOX15 P16050 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 2/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8116488 0.89 CYP1A2 (0.64) CYP1A2ALDH1A1TRPA1DGKANR1I2
SCHEMBL85568 0.89
SCHEMBL1615423 0.87 CYP1A2 (0.61) CYP1A2ALDH1A1TRPA1DGKANR1I2
SCHEMBL813481 0.86 DGKA (0.55) CYP1A2ALDH1A1TRPA1DGKANR1I2
SCHEMBL7034021 0.85 CYP1A2 (0.59) CYP1A2ALDH1A1TRPA1DGKANR1I2
SCHEMBL7028823 0.85 CYP1A2 (0.59) CYP1A2ALDH1A1TRPA1DGKANR1I2
SCHEMBL2607005 0.85 CYP1A2 (0.59) CYP1A2ALDH1A1TRPA1DGKANR1I2
SCHEMBL2607206 0.83 CYP1A2 (0.57) CYP1A2ALDH1A1TRPA1DGKANR1I2
SCHEMBL282083 0.83 CYP1A2 (0.61) CYP1A2ALDH1A1TRPA1DGKANR1I2
SCHEMBL916783 0.82 CYP1A2 (0.52) CYP1A2ALDH1A1TRPA1DGKANR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0702689-A4 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS ABBOTT LAB (US) 1997-10-22 EP disclosed
EP-0702689-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS ABBOTT LABORATORIES (US) 1996-03-27 EP disclosed
WO-1994029329-A1 HAPTENS, TRACERS, IMMUNOGENS AND ANTIBODIES FOR 3-PHENYL-1-ADAMANTANEACETIC ACIDS ABBOTT LABORATORIES (US) 1994-12-22 WO disclosed