⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8057325 | 0.93 | — | — | |
| SCHEMBL8768730 | 0.91 | — | — | |
| SCHEMBL9171155 | 0.91 | — | — | |
| SCHEMBL6430680 | 0.85 | — | — | |
| SCHEMBL1183066 | 0.82 | — | — | |
| SCHEMBL10909906 | 0.78 | — | — | |
| SCHEMBL5867297 | 0.77 | — | — | |
| SCHEMBL8999310 | 0.76 | — | — | |
| SCHEMBL9166158 | 0.76 | — | — | |
| SCHEMBL9125876 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662954-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1997-08-20 | — | — | EP | disclosed |
| EP-0675878-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1997-01-29 | — | — | EP | disclosed |
| US-5589471-A | Vitamin D analogues containing a hydroxy or alkylated hydroxy group in the 20-position | FABRIK PRODUKTIONSAKTIESELSKAB LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1996-12-31 | — | — | US | disclosed |
| US-5554599-A | ANTIINFLAMMATORY AND IMMUNOMODULATING AGENTS; PSORIASIS, OSTEOPOROSIS, OSTEOGENESIS | LEO PHARMACEUTICAL PRODUCTS LTD. (DK) | 1996-09-10 | — | — | US | disclosed |
| EP-0675878-A1 | NOVEL VITAMIN D ANALOGUES. | LEO PHARM PROD LTD (DK) | 1995-10-11 | — | — | EP | disclosed |
| US-5374629-A | A triene steroids as anticarcinogenic agents, treating skin disorders | LEO PHARMACEUTICAL PRODUCTS LTD. A/S LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1994-12-20 | — | — | US | disclosed |
| EP-0522013-B1 | NOVEL VITAMIN D ANALOGUES | LEO PHARM PROD LTD (DK) | 1994-11-23 | — | — | EP | disclosed |
| WO-1994014766-A1 | NOVEL VITAMIN D ANALOGUES | Leo Pharmaceutical Products Ltd. A/S (Løvens Kemiske Fabrik Produktionsaktieselskab) (DK) | 1994-07-07 | — | — | WO | disclosed |