⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999311 | 0.85 | — | — | |
| SCHEMBL10909906 | 0.78 | — | — | |
| SCHEMBL9166158 | 0.76 | — | — | |
| SCHEMBL8745348 | 0.76 | — | — | |
| SCHEMBL8057325 | 0.74 | — | — | |
| SCHEMBL9127732 | 0.74 | — | — | |
| SCHEMBL10986052 | 0.74 | TSHR (0.39) | — | |
| SCHEMBL11023455 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL9171155 | 0.73 | — | — | |
| SCHEMBL8768730 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572489-B1 | STARTING COMPOUNDS FOR PREPARING CALCITRIOL AND ITS DERIVATIVES, METHOD FOR PREPARING THESE STARTING COMPOUNDS AND INTERMEDIATE PRODUCTS FOR THIS METHOD | JENAPHARM GMBH (DE) | 1996-09-04 | — | — | EP | disclosed |
| EP-0572489-A1 | STARTING COMPOUNDS FOR PREPARING CALCITRIOL AND ITS DERIVATIVES, METHOD FOR PREPARING THESE STARTING COMPOUNDS AND INTERMEDIATE PRODUCTS FOR THIS METHOD. | JENAPHARM GMBH (DE) | 1993-12-08 | — | — | EP | disclosed |
| WO-1992014746-A1 | STARTING COMPOUNDS FOR PREPARING CALCITRIOL AND ITS DERIVATIVES, METHOD FOR PREPARING THESE STARTING COMPOUNDS AND INTERMEDIATE PRODUCTS FOR THIS METHOD | JENAPHARM GMBH (DE) | 1992-09-03 | — | — | WO | disclosed |