Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745367 | 0.77 | MAPT (0.45) | ALDH1A1GAAPOLBMAPK1NPSR1 | |
| SCHEMBL31519541 | 0.70 | ALDH1A1 (0.46) | ALDH1A1GAAPOLBMAPK1NPSR1 | |
| SCHEMBL8588726 | 0.69 | ALDH1A1 (0.45) | ALDH1A1GAAPOLBMAPK1NPSR1 | |
| SCHEMBL14232274 | 0.63 | UPP1 (0.57) | ALDH1A1GAAPOLBMAPK1NPSR1 | |
| SCHEMBL21082485 | 0.63 | GAA (0.45) | ALDH1A1GAAMAPK1BCHE | |
| SCHEMBL13908943 | 0.63 | UPP1 (0.57) | ALDH1A1GAAPOLBMAPK1NPSR1 | |
| SCHEMBL19132673 | 0.63 | BCHE (0.49) | ALDH1A1GAAPOLBMAPK1NPSR1 | |
| SCHEMBL20141985 | 0.63 | UPP1 (0.57) | ALDH1A1GAAPOLBMAPK1NPSR1 | |
| SCHEMBL15481924 | 0.63 | UPP1 (0.57) | ALDH1A1GAAPOLBMAPK1NPSR1 | |
| SCHEMBL21754783 | 0.63 | UPP1 (0.51) | ALDH1A1GAAPOLBMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0707590-A1 | DIDEOXYFRUCTONUCLEOTIDES AND DEOXYFRUCTONUCLEOTIDES AS DNA POLYMERASE SUBSTRATES | DU PONT (US) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001986-A1 | DIDEOXYFRUCTONUCLEOTIDES AND DEOXYFRUCTONUCLEOTIDES AS DNA POLYMERASE SUBSTRATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-19 | — | — | WO | disclosed |
| US-5276143-A | Dideoxyfructonucleosides and deoxyfructonucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-01-04 | — | — | US | disclosed |