SCHEMBL8745530

SCHEMBL8745530

CCN(CC)c1ccc(NC(=O)O)c(C)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.63
GFER P55789 5/20 0.63
HTT P42858 4/20 0.63
SMN1; SMN2 Q16637 4/20 0.63
LMNA P02545 3/20 0.63
CYP2C19 P33261 2/20 0.63
CYP1A2 P05177 1/20 0.63
MAPK1 P28482 4/20 0.61
ALDH1A1 P00352 3/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
ALOX15 P16050 2/20 0.61
NPSR1 Q6W5P4 2/20 0.61
HSD17B10 Q99714 2/20 0.60
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
POLB P06746 3/20 0.57
GAA P10253 1/20 0.57
HCRTR1 O43613 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11742710 0.89 MAPT (0.61) MAPTGFERHTTSMN1; SMN2LMNA
SCHEMBL11050769 0.87 MAPT (0.60) MAPTGFERHTTSMN1; SMN2LMNA
SCHEMBL7930582 0.84 MAPT (0.57) MAPTGFERHTTSMN1; SMN2LMNA
SCHEMBL13650236 0.83 GFER (0.62) MAPTGFERHTTSMN1; SMN2LMNA
SCHEMBL13650235 0.82 MAPT (0.58) MAPTGFERHTTSMN1; SMN2LMNA
SCHEMBL14469879 0.82 MAPT (0.55) MAPTGFERHTTSMN1; SMN2LMNA
SCHEMBL13650229 0.82 MAPT (0.61) MAPTGFERHTTSMN1; SMN2LMNA
SCHEMBL13942875 0.81 MAPT (0.57) MAPTGFERHTTSMN1; SMN2LMNA
SCHEMBL7770385 0.81 S100B (0.55) MAPTGFERHTTSMN1; SMN2LMNA
SCHEMBL653134 0.81 MAPT (0.53) MAPTGFERHTTSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0429940-B1 Method for processing silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1997-01-29 EP disclosed
US-5102778-A Using hydrophilic p-phenylenediamine derivative; high speed color development FUJI PHOTO FILM CO., LTD. (JP) 1992-04-07 US disclosed
EP-0429940-A1 Method for processing silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-06-05 EP disclosed
US-4060418-A Phenoxy carbonyl derivatives of a paraphenylenediamine color developer and their use in an image-receiving sheet for color diffusion transfer GAF CORPORATION (US) 1977-11-29 US disclosed