Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.57 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735711 | 0.85 | HTT (0.56) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL735949 | 0.85 | HTT (0.56) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL735712 | 0.85 | HTT (0.56) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL7752769 | 0.85 | LMNA (0.67) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL6465218 | 0.83 | LMNA (0.57) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL334927 | 0.82 | SLC1A3 (0.64) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL735799 | 0.82 | SLC1A3 (0.64) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL334926 | 0.82 | SLC1A3 (0.64) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL26630558 | 0.82 | LMNA (0.63) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 | |
| SCHEMBL966270 | 0.82 | LMNA (0.63) | HTTLMNASMN1; SMN2SLC1A3SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546179-B1 | 4-O-(AMINOGLYCOSYL)- OR 4,6-DI-O-(AMINOGLYCOSYL)-2,5-DIDEOXY-5,5-DIFLUOROSTREPTAMINE DERIVATIVE AND PRODUCTION THEREOF | ZAIDAN HOJIN BISEIBUTSU (JP) | 1997-02-12 | — | — | EP | disclosed |
| US-5527781-A | AMINOGLYCOSIDE ANTIBIOTICS | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1996-06-18 | — | — | US | disclosed |
| EP-0546179-A1 | 4-O-(AMINOGLYCOSYL)- OR 4,6-DI-O-(AMINOGLYCOSYL)-2,5-DIDEOXY-5,5-DIFLUOROSTREPTAMINE DERIVATIVE AND PRODUCTION THEREOF | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0259014-A2 | 5-Deoxy-5-fluorokanamycin B derivatives and processes for the production thereof | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1988-03-09 | — | — | EP | disclosed |
| US-4297485-A | Production of a selectively protected N-acylated derivative of an aminoglycosidic antibiotic | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) | 1981-10-27 | — | — | US | disclosed |