Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 5/20 | 0.62 |
| ▸ | CASP1 | P29466 | 4/20 | 0.62 |
| ▸ | CASP7 | P55210 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | CLK2 | P49760 | 1/20 | 0.51 |
| ▸ | CCR4 | P51679 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.48 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.48 |
| ▸ | IGF1R | P08069 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745801 | 0.88 | KDM4E (0.64) | KDM4EALDH1A1MAPTGAACASP1 | |
| SCHEMBL4706717 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1MAPTGAACASP1 | |
| SCHEMBL6584895 | 0.82 | KDM4E (0.79) | KDM4EALDH1A1MAPTGAACASP1 | |
| SCHEMBL5085562 | 0.81 | KDM4E (0.72) | KDM4EALDH1A1MAPTGAACASP1 | |
| SCHEMBL3782322 | 0.81 | CLK2 (0.63) | KDM4EALDH1A1MAPTGAACASP1 | |
| SCHEMBL3274825 | 0.80 | KDM4E (0.78) | KDM4EALDH1A1MAPTGAACASP1 | |
| SCHEMBL27948295 | 0.79 | CCR4 (0.63) | KDM4EALDH1A1MAPTGAACASP1 | |
| SCHEMBL3786044 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1MAPTGAACASP1 | |
| Ocimarin SCHEMBL23752453 | 0.77 | HSD17B3 (0.79) | KDM4EALDH1A1MAPTGAACASP1 | |
| SCHEMBL6583766 | 0.76 | KDM4E (0.77) | KDM4EALDH1A1MAPTGAACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663911-B1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | SCHWABE WILLMAR GMBH & CO (DE) | 1997-02-05 | — | — | EP | disclosed |
| US-5550129-A | THERAPY FOR NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | WILLMAR SCHWABE GMBH & CO. (DE) | 1996-08-27 | — | — | US | disclosed |
| EP-0663911-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE. | SCHWABE WILLMAR GMBH & CO (DE) | 1995-07-26 | — | — | EP | disclosed |
| WO-1994008985-A1 | BENZOPYRANONES, METHOD OF PREPARING THEM AND THEIR USE | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1994-04-28 | — | — | WO | disclosed |