Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28241871 | 0.82 | EPHX2 (0.49) | EPHX2TSHRNPSR1TP53CA12 | |
| SCHEMBL10523056 | 0.82 | EPHX2 (0.49) | EPHX2TSHRNPSR1TP53CA12 | |
| Hydrochloric Acid SCHEMBL28241080 | 0.81 | EPHX2 (0.47) | EPHX2TSHRNPSR1TP53CA12 | |
| SCHEMBL28883270 | 0.77 | ALDH1A1 (0.54) | EPHX2TSHRNPSR1TP53CA12 | |
| SCHEMBL27488385 | 0.76 | EPHX2 (0.51) | EPHX2TSHRNPSR1TP53CA12 | |
| SCHEMBL3017799 | 0.76 | EPHX2 (0.43) | EPHX2TSHRNPSR1TP53CA12 | |
| SCHEMBL27488748 | 0.74 | EPHX2 (0.49) | EPHX2TSHRCA12CA1CA2 | |
| SCHEMBL2484642 | 0.72 | EPHX2 (0.43) | EPHX2TSHRLMNAALDH1A1KMT2A | |
| SCHEMBL11424447 | 0.72 | EPHX2 (0.47) | EPHX2NPSR1SLC1A1SMN1; SMN2ALDH1A1 | |
| SCHEMBL12139098 | 0.71 | HDAC4 (0.46) | EPHX2CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519763-B1 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO PERFUMERY CO LTD (JP) | 1997-02-05 | — | — | EP | disclosed |
| US-5502221-A | HYPOTENSIVE INTERMEDIATE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1996-03-26 | — | — | US | disclosed |
| US-5442105-A | Catalytic hydrogenation, epoxidation, reacting product with trialkylsilyl azide in the presence of a Lewis acid, hydrogenolysis | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1995-08-15 | — | — | US | disclosed |
| EP-0519763-A2 | Cyclohexylbutyric acid derivatives and their use in the production of optically active cyclohexylnorstatine | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-12-23 | — | — | EP | disclosed |