⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19924604 | 0.81 | — | — | |
| SCHEMBL5250486 | 0.80 | — | — | |
| SCHEMBL10614405 | 0.71 | — | — | |
| SCHEMBL21987804 | 0.71 | MAPT (0.35) | — | |
| SCHEMBL1446287 | 0.68 | MEN1 (0.33) | — | |
| SCHEMBL3739006 | 0.68 | MAPT (0.33) | — | |
| SCHEMBL11497257 | 0.66 | GAA (0.36) | — | |
| SCHEMBL31406880 | 0.66 | CA1 (0.42) | — | |
| SCHEMBL8215145 | 0.66 | CA1 (0.42) | — | |
| SCHEMBL3339305 | 0.65 | MAPT (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0457182-B1 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | BOEHRINGER MANNHEIM GMBH (DE) | 1997-02-26 | — | — | EP | disclosed |
| EP-0457182-A2 | Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor | Roche Diagnostics GmbH (DE) | 1991-11-21 | — | — | EP | disclosed |