SCHEMBL21987804

SCHEMBL21987804

Nc1c(Br)c(Br)c(N)c(Br)c1Br

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
GAA P10253 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3739006 0.95 MAPT (0.33) MAPTGAANPSR1
SCHEMBL3339305 0.91 MAPT (0.32) MAPTGAANPSR1
SCHEMBL23671721 0.84 MAPT (0.33) MAPTGAANPSR1
SCHEMBL15572589 0.78 GAA (0.35) MAPTGAA
SCHEMBL21869874 0.75 AKR1B1 (0.31) MAPTNPSR1
SCHEMBL9438204 0.73 CA1 (0.33)
SCHEMBL8746006 0.71
SCHEMBL17262654 0.71 MAPT (0.47) MAPTGAANPSR1
SCHEMBL21963176 0.67 LMNA (0.55) MAPTGAA
SCHEMBL16079767 0.65 CA1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112409998-A Photo-thermal conversion eutectic material containing N, N, N, N-tetramethyl-p-phenylenediamine and preparation method thereof 汕头大学 2021-02-26 CN claimed
US-10899884-B2 Flame-retardant polyetheretherketone-based compounds INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2021-01-26 US disclosed
US-20200172668-A1 FLAME-RETARDANT POLYETHERETHERKETONE-BASED COMPOUNDS INTERNATIONAL BUSINESS MACHINES CORPORATION 2020-06-04 US disclosed