SCHEMBL8746013

SCHEMBL8746013

CC(C)C1=CC2=CCC3[C@@](C)(COC[C@@]4(C)CCC[C@@]5(C)C4CC=C4C=C(C(C)C)CC[C@H]45)CCC[C@]3(C)[C@@H]2CC1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 5/20 0.77
▸ ALDH1A1 P00352 2/20 0.77
▸ LMNA P02545 2/20 0.77
▸ MAPK1 P28482 2/20 0.77
▸ CYP3A4 P08684 4/20 0.62
▸ HSD17B10 Q99714 3/20 0.62
▸ PDK1 Q15118 3/20 0.62
▸ PDK2 Q15119 3/20 0.62
▸ PDK3 Q15120 3/20 0.62
▸ PDK4 Q16654 3/20 0.62
▸ MAPT P10636 3/20 0.62
▸ CYP2C9 P11712 2/20 0.62
▸ CYP2C19 P33261 2/20 0.62
▸ SLCO1B3 Q9NPD5 1/20 0.62
▸ SLCO1B1 Q9Y6L6 1/20 0.62
▸ GABRA1 P14867 1/20 0.62
▸ GABRB2 P47870 1/20 0.62
▸ KDM4E B2RXH2 1/20 0.62
▸ MEN1 O00255 3/20 0.48
▸ KMT2A Q03164 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8746011 1.00 ALOX15 (0.77) ALOX15ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL12417300 0.90 ALOX15 (0.66) ALOX15ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL2189006 0.90 ALOX15 (0.66) ALOX15ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL2189010 0.90 ALOX15 (0.66) ALOX15ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL8961449 0.89 ALOX15 (0.71) ALOX15ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL8961448 0.89 ALOX15 (0.71) ALOX15ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL19027534 0.88 ALOX15 (0.70) ALOX15ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL2447910 0.87 ALOX15 (0.72) ALOX15ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL2447909 0.87 ALOX15 (0.72) ALOX15ALDH1A1LMNAMAPK1CYP3A4
SCHEMBL6536466 0.87 ALOX15 (0.79) ALOX15ALDH1A1LMNAMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1155100-A Photosensitive composition and photosensitive lithographic printing plate using the same KONISHIROKU PHOTO IND (JP) 1997-07-23 — — CN disclosed
EP-0484087-B1 Method and apparatus for processing presensitized lithographic printing plate KONISHIROKU PHOTO IND (JP) 1997-01-02 — — EP disclosed
EP-0484087-A2 Method and apparatus for processing presensitized lithographic printing plate KONICA CORPORATION (JP) 1992-05-06 — — EP disclosed
US-4879197-A ANTIFOGGING AGENTS MITSUBISHI PAPER MILLS, LTD. (JP) 1989-11-07 — — US disclosed
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