Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 8/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 8/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.30 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874316 | 0.86 | HSP90AA1 (0.35) | HSP90AA1P2RX7PPARAKCNH2PPARG | |
| SCHEMBL882995 | 0.85 | P2RX7 (0.40) | HSP90AA1P2RX7PPARAKCNH2PPARG | |
| SCHEMBL5020366 | 0.84 | CCR1 (0.41) | HSP90AA1P2RX7PPARAKCNH2PPARG | |
| SCHEMBL874223 | 0.84 | HSP90AA1 (0.33) | HSP90AA1P2RX7HKDC1DUSP3PTPN11 | |
| SCHEMBL882865 | 0.83 | HSP90AA1 (0.38) | HSP90AA1P2RX7PPARAKCNH2PPARG | |
| SCHEMBL10273698 | 0.83 | HSP90AA1 (0.38) | HSP90AA1P2RX7PPARAKCNH2PPARG | |
| SCHEMBL882894 | 0.83 | HSP90AA1 (0.38) | HSP90AA1P2RX7PPARAKCNH2PPARG | |
| SCHEMBL5020358 | 0.83 | HSP90AA1 (0.36) | HSP90AA1P2RX7KCNH2HKDC1DUSP3 | |
| SCHEMBL15464235 | 0.82 | GRM5 (0.37) | HSP90AA1P2RX7PPARAKCNH2PPARG | |
| SCHEMBL5020378 | 0.82 | GRM5 (0.37) | HSP90AA1P2RX7PPARAKCNH2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619181-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038521-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-03-29 | — | — | WO | disclosed |