SCHEMBL8746180

SCHEMBL8746180

[CH2]CCC(=O)CCCC(=O)CC

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.43
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
IAPP P10997 1/20 0.31
FFAR3 O14843 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HAO1 Q9UJM8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27554524 0.90 TDP1 (0.47) TDP1MAPTKMT2ACES2CES1
SCHEMBL131716 0.89
SCHEMBL27605326 0.85 MAPT (0.43) MAPTKMT2ACES2CES1IAPP
SCHEMBL133771 0.84
SCHEMBL23735973 0.84 TDP1 (0.53) TDP1MAPTKMT2ALMNACES2
SCHEMBL1771453 0.84 TDP1 (0.60) TDP1MAPTKMT2ALMNACES2
SCHEMBL128613 0.82
SCHEMBL27570895 0.82 TDP1 (0.45) TDP1MAPTKMT2ALMNACES2
SCHEMBL1412938 0.82
SCHEMBL128010 0.80 TDP1 (0.43) TDP1MAPTKMT2ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1318419-C 1,6,9,14-tetrasubstituted terrylene tetracarboxylic acid diimides BASF AG (DE) 2007-05-30 CN disclosed
CN-1659167-A 1,6,9,14-tetrasubstituted terrylene tetracarboxylic acid diimides BASF AG (DE) 2005-08-24 CN disclosed
CN-1525953-A Method for producing (meth) acrylic acid esters �����ɷ� 2004-09-01 CN disclosed
EP-0640116-B1 AZO DYES WITH AN ACETALISED DIAZO COMPONENT FROM THE THIOPHENE O R THIAZOL SERIES BASF AG (DE) 1997-02-12 EP disclosed
EP-0640116-A1 AZO DYES WITH AN ACETALISED DIAZO COMPONENT FROM THE THIOPHENE O R THIAZOL SERIES. BASF AG (DE) 1995-03-01 EP disclosed
WO-1993023479-A1 AZO DYES WITH AN ACETALISED DIAZO COMPONENT FROM THE THIOPHENE O R THIAZOL SERIES BASF AKTIENGESELLSCHAFT (DE) 1993-11-25 WO disclosed