⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27554524 | 0.94 | TDP1 (0.47) | — | |
| SCHEMBL8746180 | 0.89 | TDP1 (0.43) | — | |
| SCHEMBL133771 | 0.82 | — | — | |
| SCHEMBL128613 | 0.80 | — | — | |
| SCHEMBL619312 | 0.79 | TDP1 (0.69) | — | |
| SCHEMBL6932133 | 0.79 | — | — | |
| SCHEMBL127466 | 0.79 | — | — | |
| SCHEMBL8061372 | 0.79 | TDP1 (0.50) | — | |
| SCHEMBL128010 | 0.78 | TDP1 (0.43) | — | |
| SCHEMBL7839683 | 0.78 | TDP1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 265 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112834647-A | Method for determining 297 pesticide residues by combining pretreatment technology of high-oil complex matrix sample with GC-MSMS (gas chromatography-metal-semiconductor mass spectrometry) | 中国检验检疫科学研究院 | 2021-05-25 | — | — | CN | claimed |
| EP-3558980-B1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | C N C C S S C A R L COLLEZIONE NAZ DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2021-01-27 | — | — | EP | claimed |
| US-10815222-B2 | Compounds for use in the treatment of kinetoplastid infection | C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2020-10-27 | — | — | US | claimed |
| US-20200095232-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | C.N.C.C.S. S.C.A.R.L. COLLEZIONE NAZIONALE DEI COMPOSTI CHIMICI E CENTRO SCREENING (IT) | 2020-03-26 | — | — | US | claimed |
| EP-3558980-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | C.N.C.C.S. S.c.a.r.l. Collezione Nazionale Dei Composti Chimici e Centro Screening (IT) | 2019-10-30 | — | — | EP | claimed |
| WO-2018115275-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF KINETOPLASTID INFECTION | IRBM SCIENCE PARK S.P.A. (IT) | 2018-06-28 | — | — | WO | claimed |
| US-20140038181-A1 | CHEMICALLY SUBSTITUTED THERMOSENSITIVE PROBES AND COFACTORS FOR HOT START LIGATION | TRILINK BIOTECHNOLOGIES, INC. | 2014-02-06 | — | — | US | claimed |
| US-8361753-B2 | Phosphotriester-modified oligonucleotide primers for nucleic acid amplification | TRILINK BIOTECHNOLOGIES, INC. (US) | 2013-01-29 | — | — | US | claimed |
| WO-2012094343-A1 | CHEMICALLY SUBSTITUTED THERMOSENSITIVE PROBES AND COFACTORS FOR HOT START LIGATION | TRILINK BIOTECHNOLOGIES (US) | 2012-07-12 | — | — | WO | claimed |
| EP-2032714-B1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDE PRIMERS FOR NUCLEIC ACID AMPLIFICATION | TRILINK BIOTECHNOLOGIES (US) | 2011-03-16 | — | — | EP | claimed |
| CN-101632741-A | Quality Control Method of Jianer Qingjie Liquid | BEIJING ASIA EAST BIO PHARM CO | 2010-01-27 | — | — | CN | claimed |
| EP-2032714-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDE PRIMERS FOR NUCLEIC ACID AMPLIFICATION | TriLink BioTechnologies (US) | 2009-03-11 | — | — | EP | claimed |
| CN-101301353-A | Preparation of Dandengtongnao medicinal formulation and quality control method | CHUANLIANG HU (CN) | 2008-11-12 | — | — | CN | claimed |
| WO-2007139723-A1 | CHEMICALLYMODIFIED OLIGONUCLEOTIDE PRIMERS FOR NUCLEIC ACID AMPLIFICATION | TRILINK BIOTECHNOLOGIES (US) | 2007-12-06 | — | — | WO | claimed |
| US-20070281308-A1 | CHEMICALLY MODIFIED OLIGONUCLEOTIDE PRIMERS FOR NUCLEIC ACID AMPLIFICATION | TRILINK BIOTECHNOLOGIES, LLC | 2007-12-06 | — | — | US | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005037797-A1 | SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-28 | — | — | WO | claimed |
| CN-1397588-A | Photocationic solidified resin compsn. and its application | MITSUI CHEMICALS INC (JP) | 2003-02-19 | — | — | CN | claimed |
| CN-115175967-B | Ionic liquids for stabilizing viscosity of silicate-based coatings | 巴斯夫欧洲公司 | 2024-06-14 | — | — | CN | disclosed |
| US-3983117-A | OPTICAL BRIGHTENERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-09-28 | — | — | US | disclosed |