Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.77 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.73 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2905098 | 1.00 | MEN1 (0.77) | MEN1KMT2ALTB4R2ALOX5MAPT | |
| SCHEMBL5579187 | 1.00 | MEN1 (0.77) | MEN1KMT2ALTB4R2ALOX5MAPT | |
| SCHEMBL4329512 | 1.00 | MEN1 (0.77) | MEN1KMT2ALTB4R2ALOX5MAPT | |
| SCHEMBL7718097 | 1.00 | MEN1 (0.77) | MEN1KMT2ALTB4R2ALOX5MAPT | |
| SCHEMBL5579185 | 1.00 | MEN1 (0.77) | MEN1KMT2ALTB4R2ALOX5MAPT | |
| SCHEMBL4329518 | 1.00 | MEN1 (0.77) | MEN1KMT2ALTB4R2ALOX5MAPT | |
| SCHEMBL16718910 | 0.99 | MEN1 (0.76) | MEN1KMT2ALTB4R2ALOX5MAPT | |
| SCHEMBL16718912 | 0.99 | MEN1 (0.76) | MEN1KMT2ALTB4R2ALOX5MAPT | |
| SCHEMBL10699234 | 0.96 | MEN1 (0.84) | MEN1KMT2ALTB4R2ALOX5MAPT | |
| SCHEMBL29926784 | 0.96 | MEN1 (0.84) | MEN1KMT2ALTB4R2ALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469075-B1 | USE OF LIPOXIN A 4? AND ITS DERIVATIVES AS ANTAGONISTS FOR SLOW-REACTING SUBSTANCES OF ANAPHYLAXIS | BRIGHAM & WOMENS HOSPITAL (US) | 1997-01-08 | — | — | EP | disclosed |
| EP-0469075-A4 | USE OF LIPOXIN A 4? AND ITS DERIVATIVES AS ANTAGONISTS FOR SLOW-REACTING SUBSTANCES OF ANAPHYLAXIS | — | 1992-09-09 | — | — | EP | disclosed |
| EP-0469075-A1 | USE OF LIPOXIN A 4? AND ITS DERIVATIVES AS ANTAGONISTS FOR SLOW-REACTING SUBSTANCES OF ANAPHYLAXIS. | BRIGHAM & WOMENS HOSPITAL (US) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990013292-A1 | USE OF LIPOXIN A4 AND ITS DERIVATIVES AS ANTAGONISTS FOR SLOW-REACTING SUBSTANCES OF ANAPHYLAXIS | BRIGHAM AND WOMEN'S HOSPITAL (US) | 1990-11-15 | — | — | WO | disclosed |