SCHEMBL5579187

SCHEMBL5579187

CCCCCC(C=CC=CCC=CCC=CCCCC(=O)O)OO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.77
KMT2A Q03164 1/20 0.77
LTB4R2 Q9NPC1 1/20 0.73
ALOX5 P09917 2/20 0.65
MAPT P10636 1/20 0.65
OXER1 Q8TDS5 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2905098 1.00 MEN1 (0.77) MEN1KMT2ALTB4R2ALOX5MAPT
SCHEMBL4329512 1.00 MEN1 (0.77) MEN1KMT2ALTB4R2ALOX5MAPT
SCHEMBL7718097 1.00 MEN1 (0.77) MEN1KMT2ALTB4R2ALOX5MAPT
SCHEMBL8746346 1.00 MEN1 (0.77) MEN1KMT2ALTB4R2ALOX5MAPT
SCHEMBL5579185 1.00 MEN1 (0.77) MEN1KMT2ALTB4R2ALOX5MAPT
SCHEMBL4329518 1.00 MEN1 (0.77) MEN1KMT2ALTB4R2ALOX5MAPT
SCHEMBL16718910 0.99 MEN1 (0.76) MEN1KMT2ALTB4R2ALOX5MAPT
SCHEMBL16718912 0.99 MEN1 (0.76) MEN1KMT2ALTB4R2ALOX5MAPT
SCHEMBL10699234 0.96 MEN1 (0.84) MEN1KMT2ALTB4R2ALOX5MAPT
SCHEMBL29926784 0.96 MEN1 (0.84) MEN1KMT2ALTB4R2ALOX5MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899485-A Pharmaceutically acceptable salts of polyunsaturated hydroxy fatty acids 尊严科学有限公司 2016-08-24 CN claimed
WO-2022102788-A1 COMPOSITION FOR ENHANCING ADRENOMEDULLIN GENE EXPRESSION ハウスウェルネスフーズ株式会社 2022-05-19 WO disclosed
US-10197498-B2 Compositions and methods for measurement of analytes NORTHEASTERN UNIVERSITY (US) 2019-02-05 US disclosed
CN-109232278-A The pharmaceutically acceptable salt of how unsaturated hydroxy fatty acid DS生物制药有限公司 2019-01-18 CN disclosed
US-20160274030-A1 COMPOSITIONS AND METHODS FOR MEASUREMENT OF ANALYTES NORTHEASTERN UNIVERSITY (US) 2016-09-22 US disclosed
CN-105899485-A Pharmaceutically acceptable salts of polyunsaturated hydroxy fatty acids 尊严科学有限公司 2016-08-24 CN disclosed
WO-2015061371-A1 COMPOSITIONS AND METHODS FOR MEASUREMENT OF ANALYTES NORTHEASTERN UNIVERSITY (US) 2015-04-30 WO disclosed
US-20070122865-A1 Enzymes and enzymic processes NANOBIODESIGN LIMITED (GB) 2007-05-31 US disclosed
US-6894059-B1 Compounds and methods for treatment of asthma, allergy and inflammatory disorders UCB S.A. (BE) 2005-05-17 US disclosed
EP-1165533-B1 COMPOUNDS AND METHODS FOR TREATMENT OF ASTHMA, ALLERGY AND INFLAMMATORY DISORDERS UCB SA (BE) 2004-10-13 EP disclosed
EP-1414950-A2 CHIMERIC PROTEINS COMPRISING A HAEM DOMAIN OF A MAMMALIAN OR PLANT CYTOCHROME P450 AND A SCAFFOLD-REDUCTASE DOMAIN FROM P450 BM3 OF BACILLUS MEGATERIUM AND USES THEREOF NanoBioDesign Limited (GB) 2004-05-06 EP disclosed
US-20040048875-A1 Compounds and methods for treatment of asthma, allergy and inflammatory disorders UCB S.A. 2004-03-11 US disclosed
US-6686502-B1 N-HYDROXYL-N-(3-BUTYNYL)-UREA CHEMICAL INTERMEDIATE FOR PIPERIDINE OR PIPERAZINE DERIVATIVES UCB S.A. (BE) 2004-02-03 US disclosed
US-20030220347-A1 Compounds and methods for treatment of asthma, allergy and inflammatory disorders UCB S.A. 2003-11-27 US disclosed
WO-2003014341-A2 CHIMERIC PROTEINS COMPRISING A HAEM DOMAIN OF A MAMMALIAN OR PLANT CYTOCHROME P450 AND A SCAFFOLD-REDUCTASE DOMAIN FROM P450 BM3 OF BACILLUS MEGATERIUM AND USES THEREOF NANOBIODESIGN LIMITED (GB) 2003-02-20 WO disclosed
CN-1387503-A Hydroxyeicosatetraenoate salts, composition and method of use in treating dry eye disorders ALCON UNIVERSAL LTD (CH) 2002-12-25 CN disclosed
CN-1387505-A Compositions contg. hydroxyeicosatetraenoic acid derivs, and methods of use in treating dry eye disorders ALCON UNIVERSAL LTD (CH) 2002-12-25 CN disclosed
US-6451801-B1 1,4-SUBSTITUTED PIPERIDINES AND PIPERAZINES UCB, S.A. (BE) 2002-09-17 US disclosed
EP-1165533-A2 COMPOUNDS AND METHODS FOR TREATMENT OF ASTHMA, ALLERGY AND INFLAMMATORY DISORDERS UCB, S.A. (BE) 2002-01-02 EP disclosed
WO-2000058295-A2 COMPOUNDS AND METHODS FOR TREATMENT OF ASTHMA, ALLERGY AND INFLAMMATORY DISORDERS UCB, S.A. (BE) 2000-10-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220347-A1 Compounds and methods for treatment of asthma, allergy and inflammatory disorders HRH4, HRH2, HRH3 MEN1 2857/4885KMT2A 2264/4885LTB4R2 6/4885
US-20070122865-A1 Enzymes and enzymic processes BLVRB, CYP4F3, POR MEN1 3080/4885KMT2A 4529/4885LTB4R2 2921/4885
US-20040048875-A1 Compounds and methods for treatment of asthma, allergy and inflammatory disorders HRH4, HRH2, HRH3 MEN1 2857/4885KMT2A 2264/4885LTB4R2 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.