Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776782 | 1.00 | ELANE (0.49) | ELANEKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL8746491 | 0.87 | ELANE (0.66) | ELANEPOLBRIPK1ALDH1A1 | |
| SCHEMBL7776803 | 0.87 | ELANE (0.66) | ELANEPOLBRIPK1ALDH1A1 | |
| SCHEMBL7779914 | 0.85 | ELANE (0.52) | ELANEKMT2AMEN1RIPK1 | |
| SCHEMBL7778739 | 0.84 | ELANE (0.48) | ELANEKMT2AMEN1POLBRIPK1 | |
| SCHEMBL7776769 | 0.82 | ELANE (0.47) | ELANEKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL7778734 | 0.82 | ELANE (0.47) | ELANEKMT2AMEN1L3MBTL1RIPK1 | |
| SCHEMBL4366611 | 0.82 | ELANE (0.49) | ELANEKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL5887457 | 0.82 | ELANE (0.49) | ELANEKMT2AMEN1POLBL3MBTL1 | |
| SCHEMBL5887453 | 0.82 | ELANE (0.49) | ELANEKMT2AMEN1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0809627-A1 | NOVEL BORNEOL DERIVATIVES, METHODS OF MANUFACTURING THEM, AND THEIR PHARMACEUTICAL USE | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-03 | — | — | EP | disclosed |
| WO-1997035839-A1 | NOVEL BORNEOLS, PROCESSES FOR PRODUCING THEM AND PHARMACEUTICAL USE THEREOF | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |
| EP-0758316-A1 | BORNEOL DERIVATIVES AFFECTING TUBULIN POLYMERIZATION AND DEPOLYMERIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-02-19 | — | — | EP | disclosed |