Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776803 | 1.00 | ELANE (0.66) | ELANEALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7779914 | 0.87 | ELANE (0.52) | ELANEKDM4ERIPK1 | |
| SCHEMBL7776782 | 0.87 | ELANE (0.49) | ELANEALDH1A1POLBRIPK1 | |
| SCHEMBL8746478 | 0.87 | ELANE (0.49) | ELANEALDH1A1POLBRIPK1 | |
| SCHEMBL7778739 | 0.86 | ELANE (0.48) | ELANEPOLBRIPK1LMNANPSR1 | |
| SCHEMBL7776769 | 0.85 | ELANE (0.47) | ELANEALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL7778734 | 0.85 | ELANE (0.47) | ELANEALDH1A1KDM4ERIPK1LMNA | |
| SCHEMBL7772596 | 0.84 | ELANE (0.46) | ELANERIPK1 | |
| SCHEMBL7779915 | 0.84 | ELANE (0.46) | ELANERIPK1LMNA | |
| SCHEMBL7779017 | 0.84 | ELANE (0.46) | ELANEPOLBESR1ESR2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758316-A1 | BORNEOL DERIVATIVES AFFECTING TUBULIN POLYMERIZATION AND DEPOLYMERIZATION | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-02-19 | — | — | EP | disclosed |