Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 15/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | CCKAR | P32238 | 13/20 | 0.56 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746502 | 1.00 | CCKBR (0.62) | CCKBRKCNH2CCKARSCN9A | |
| SCHEMBL8746530 | 0.91 | CCKBR (0.75) | CCKBRKCNH2CCKARSCN9A | |
| SCHEMBL8746541 | 0.91 | CCKBR (0.75) | CCKBRKCNH2CCKARSCN9A | |
| SCHEMBL10435092 | 0.91 | CCKBR (0.75) | CCKBRKCNH2CCKARSCN9A | |
| SCHEMBL8746517 | 0.85 | CCKBR (0.80) | CCKBRKCNH2CCKARSCN9A | |
| SCHEMBL8746581 | 0.85 | CCKBR (0.80) | CCKBRKCNH2CCKARSCN9A | |
| SCHEMBL8536733 | 0.82 | CCKBR (0.59) | CCKBRCCKARSCN9A | |
| SCHEMBL8536728 | 0.82 | CCKBR (0.59) | CCKBRCCKARSCN9A | |
| SCHEMBL8761230 | 0.81 | CCKBR (0.79) | CCKBRKCNH2CCKARSCN9A | |
| SCHEMBL8746503 | 0.80 | CCKBR (0.45) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349949-B1 | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-01-08 | — | — | EP | disclosed |
| US-5382664-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5264433-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| EP-0349949-A2 | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |