Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CCKBR | P32239 | 10/20 | 0.53 |
| ▸ | CCKAR | P32238 | 7/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746546 | 1.00 | MEN1 (1.00) | MEN1ALDH1A1KMT2AMAPK1CCKBR | |
| SCHEMBL8211856 | 0.87 | MEN1 (0.77) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL10513690 | 0.86 | MEN1 (0.75) | MEN1ALDH1A1KMT2AMAPK1CCKBR | |
| SCHEMBL31010771 | 0.86 | MEN1 (0.75) | MEN1ALDH1A1KMT2AMAPK1CCKBR | |
| SCHEMBL20098131 | 0.78 | MEN1 (0.64) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL10373739 | 0.78 | MEN1 (0.64) | MEN1ALDH1A1KMT2AMAPK1CCKBR | |
| SCHEMBL9525158 | 0.78 | CCKBR (0.66) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL9525149 | 0.78 | CCKBR (0.66) | MEN1ALDH1A1KMT2ACCKBRCCKAR | |
| SCHEMBL642974 | 0.77 | CCKBR (0.72) | CCKBRCCKAR | |
| SCHEMBL29766969 | 0.77 | CCKBR (0.72) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349949-B1 | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-01-08 | — | — | EP | disclosed |
| US-5382664-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5264433-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-11-23 | — | — | US | disclosed |
| US-4970207-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) | 1990-11-13 | — | — | US | disclosed |
| EP-0349949-A2 | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-01-10 | — | — | EP | disclosed |
| US-3984545-A | 3,4-DIHYDROXY-PHENYL-1-ANALINE WITH BENZODIAZEPINES | THE UPJOHN COMPANY (US) | 1976-10-05 | — | — | US | disclosed |