Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGFR | P43088 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30665841 | 0.89 | KDM4E (0.46) | KDM4ELMNACA1CA2NFKB1 | |
| SCHEMBL76919 | 0.89 | KDM4E (0.46) | KDM4ELMNACA1CA2NFKB1 | |
| SCHEMBL765995 | 0.83 | CYP1B1 (0.54) | KDM4ELMNACA1CA2NFKB1 | |
| SCHEMBL1614148 | 0.83 | ERN1 (0.61) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL765996 | 0.83 | CYP1B1 (0.54) | KDM4ELMNACA1CA2NFKB1 | |
| SCHEMBL1450843 | 0.83 | ERN1 (0.61) | KDM4ECA1CA2NFKB1CA4 | |
| SCHEMBL28492967 | 0.81 | CYP1A2 (0.47) | KDM4ELMNACA1CA2NFKB1 | |
| SCHEMBL7396138 | 0.81 | MAOB (0.65) | KDM4ELMNACA1CA2NFKB1 | |
| SCHEMBL7396139 | 0.81 | MAOB (0.65) | KDM4ELMNACA1CA2NFKB1 | |
| Acrylic Acid SCHEMBL7711610 | 0.81 | KDM4E (0.40) | KDM4ELMNACA1CA2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644232-B1 | Free radical cured rubber | GOODYEAR TIRE & RUBBER (US) | 1997-03-05 | — | — | EP | claimed |