Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | TYR | P14679 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.56 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | TACR2 | P21452 | 2/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746728 | 1.00 | ALOX5 (0.59) | ALOX5CYP3A4TYRTP53MAPT | |
| SCHEMBL10438718 | 0.90 | ALOX5 (0.60) | ALOX5CYP3A4TYRTP53MAPT | |
| SCHEMBL19854457 | 0.88 | TP53 (0.54) | ALOX5CYP3A4TYRTP53MAPT | |
| SCHEMBL19854385 | 0.88 | TP53 (0.54) | ALOX5CYP3A4TYRTP53MAPT | |
| SCHEMBL20407416 | 0.86 | CYP3A4 (0.51) | ALOX5CYP3A4TYRTP53MAPT | |
| SCHEMBL28182776 | 0.85 | TYR (0.51) | ALOX5CYP3A4TYRTP53MAPT | |
| SCHEMBL10441218 | 0.83 | ESR1 (0.53) | ALOX5CYP3A4TYRTP53MAPT | |
| SCHEMBL10441002 | 0.83 | ESR1 (0.53) | ALOX5CYP3A4TYRTP53MAPT | |
| SCHEMBL27434597 | 0.83 | ESR1 (0.53) | ALOX5CYP3A4TYRTP53MAPT | |
| SCHEMBL28138649 | 0.83 | ESR1 (0.53) | ALOX5CYP3A4TYRTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760251-A1 | A membrane and method for the separation of aromatic hydrocarbons from a mixture of various aromatic hydrocarbons or from a mixture of such aromatic hydrocarbons and non-aromatic hydrocarbons | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST-NATUURWETENSCHAPPELIJK ONDERZOEK TNO (NL) | 1997-03-05 | — | — | EP | disclosed |