Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | CD38 | P28907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746770 | 0.90 | BTK (0.47) | BTKIRAK4CD38 | |
| SCHEMBL8914933 | 0.90 | BTK (0.47) | BTKIRAK4CD38 | |
| SCHEMBL8746781 | 0.88 | BTK (0.46) | BTKIRAK4 | |
| SCHEMBL8746780 | 0.88 | BTK (0.46) | BTKIRAK4 | |
| SCHEMBL8483787 | 0.87 | BTK (0.37) | BTKIRAK4 | |
| SCHEMBL8766684 | 0.87 | BTK (0.37) | BTKIRAK4 | |
| SCHEMBL8488266 | 0.85 | KMT2A (0.41) | BTK | |
| SCHEMBL8488267 | 0.85 | KMT2A (0.41) | BTK | |
| SCHEMBL27546259 | 0.85 | ABL1 (0.43) | — | |
| SCHEMBL8767927 | 0.84 | BTK (0.36) | BTKIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691321-A | INSECTICIDES, MITICIDES, PARASITICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-11-25 | — | — | US | disclosed |
| EP-0759909-A1 | HETEROCYCLYLAMINO- AND HETEROCYCLYLOXY-CYCLOALKYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES | Hoechst Schering AgrEvo GmbH (DE) | 1997-03-05 | — | — | EP | disclosed |
| WO-1995031441-A1 | HETEROCYCLYLAMINO- AND HETEROCYCLYLOXY-CYCLOALKYL DERIVATIVES, THEIR PREPARATION AND THEIR USE AS PESTICIDES AND FUNGICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1995-11-23 | — | — | WO | disclosed |