Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 14/20 | 0.47 |
| ▸ | CD38 | P28907 | 2/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746770 | 1.00 | BTK (0.47) | BTKCD38PDE7AIRAK4 | |
| SCHEMBL8746756 | 0.90 | BTK (0.41) | BTKCD38IRAK4 | |
| SCHEMBL8746781 | 0.88 | BTK (0.46) | BTKPDE7AIRAK4 | |
| SCHEMBL8746780 | 0.88 | BTK (0.46) | BTKPDE7AIRAK4 | |
| Bicarbonate SCHEMBL8746772 | 0.86 | KDM4E (0.43) | — | |
| SCHEMBL8488267 | 0.85 | KMT2A (0.41) | BTK | |
| SCHEMBL8488266 | 0.85 | KMT2A (0.41) | BTK | |
| SCHEMBL8483787 | 0.85 | BTK (0.37) | BTKIRAK4 | |
| SCHEMBL8766684 | 0.85 | BTK (0.37) | BTKIRAK4 | |
| SCHEMBL8486785 | 0.84 | BTK (0.42) | BTKCD38IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5691321-A | INSECTICIDES, MITICIDES, PARASITICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1997-11-25 | — | — | US | disclosed |