Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AGBL2 | Q5U5Z8 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582588 | 0.85 | SIRT3 (0.47) | NAPRTSIRT3TDP1RXRARXRB | |
| SCHEMBL26337351 | 0.83 | SIRT3 (0.50) | SIRT3TDP1KDM4EMAPTKDM4C | |
| SCHEMBL23599089 | 0.81 | NPSR1 (0.53) | SIRT3TDP1NPSR1P4HTMCCNC | |
| SCHEMBL3443861 | 0.81 | NAPRT (0.47) | NAPRTKDM4ECYP1A2MAPTAKR1B1 | |
| SCHEMBL11459066 | 0.81 | NAPRT (0.47) | NAPRTTDP1KDM4ECYP1A2MAPT | |
| SCHEMBL15434658 | 0.80 | CCNC (0.42) | SIRT3TDP1KDM4EMAPTCCNC | |
| Hydrochloric Acid SCHEMBL31306537 | 0.79 | NAPRT (0.46) | NAPRTKDM4ECYP1A2MAPTAKR1B1 | |
| Hydrochloric Acid SCHEMBL21198656 | 0.79 | NAPRT (0.46) | NAPRTKDM4ECYP1A2MAPTAKR1B1 | |
| SCHEMBL21241288 | 0.79 | SIRT3 (0.39) | SIRT3TDP1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL8580162 | 0.79 | PKM (0.43) | SIRT3TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2021072156-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |
| EP-0751937-A1 | N-(BENZHYDRYLOXYALKYL)-4-(CARBOXY/CARBAMOYL-METHYL)-PIPERIDINE DERIVATIVES AS ANTIDEPRESSANTS | COOPERATION PHARMACEUTIQUE FRANCAISE (FR) | 1997-01-08 | — | — | EP | disclosed |
| WO-1995026336-A1 | N-(BENZHYDRYLOXYALKYL)-4-(CARBOXY/CARBAMOYL-METHYL)-PIPERIDINE DERIVATIVES AS ANTIDEPRESSANTS | COOPERATION PHARMACEUTIQUE FRANCAISE (FR) | 1995-10-05 | — | — | WO | disclosed |