SCHEMBL8747193

SCHEMBL8747193

O=C1CCC(C(=O)O)S1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9698469 1.00
SCHEMBL21648090 0.86 POLB (0.33)
SCHEMBL8747334 0.74 TLR4 (0.32)
SCHEMBL68915 0.68 TSHR (0.33)
SCHEMBL2807157 0.68 TSHR (0.33)
SCHEMBL19743821 0.67
SCHEMBL21648209 0.64 FOLH1 (0.42)
SCHEMBL21648235 0.64 GABRP (0.39)
SCHEMBL69554 0.64 KDM4E (0.34)
SCHEMBL28613071 0.64 KDM4E (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250100997-A1 PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2025-03-27 US disclosed
EP-4463448-A1 PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2024-11-20 EP disclosed
CN-118541362-A Pyridazinylamino derivatives as ALK5 inhibitors 奇斯药制品公司 2024-08-23 CN disclosed
WO-2023135107-A1 PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2023-07-20 WO disclosed
US-20200031796-A1 COMPOSITION COMPRISING A COMPOUND OF THIOLACTONE TYPE AND A PARTICULAR SOLVENT AND PROCESS FOR TREATING KERATIN MATERIALS WITH THE COMPOSITION L'OREAL (FR) 2020-01-30 US disclosed
WO-2018115091-A1 COMPOSITION COMPRISING BISTHIOLACTONES AND PROCESS FOR TREATING KERATIN MATERIALS USING SAME L'OREAL (FR) 2018-06-28 WO disclosed
EP-0548186-B1 CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES BEECHAM GROUP PLC (GB) 1997-03-05 EP disclosed
WO-1992004353-A1 CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES BEECHAM GROUP PLC (GB) 1992-03-19 WO disclosed