SCHEMBL8747227

SCHEMBL8747227

C=CCOCCO[Si](C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.43
POLB P06746 1/20 0.43
KMT2A Q03164 1/20 0.43
ALDH1A1 P00352 1/20 0.35
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 1/20 0.31
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153914 0.79 POLB (0.52) MEN1POLBKMT2AALDH1A1CA1
SCHEMBL17739984 0.79 DUT (0.39) MEN1POLBKMT2AALDH1A1
SCHEMBL336085 0.76
SCHEMBL177611 0.76 POLB (0.50) MEN1POLBKMT2AALDH1A1CA1
SCHEMBL39378 0.76 POLB (0.50) MEN1POLBKMT2AALDH1A1CA1
SCHEMBL7521085 0.76 POLB (0.50) MEN1POLBKMT2AALDH1A1CA1
SCHEMBL15502205 0.76 POLB (0.50) MEN1POLBKMT2AALDH1A1CA1
SCHEMBL8033989 0.76 POLB (0.50) MEN1POLBKMT2AALDH1A1CA1
SCHEMBL8753814 0.76 POLB (0.50) MEN1POLBKMT2AALDH1A1CA1
SCHEMBL16491142 0.76 POLB (0.50) MEN1POLBKMT2AALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573815-B Quick-crosslinking-curing MQ type silicon resin and preparation method and application thereof 杭州师范大学 2023-07-25 CN claimed
CN-114409903-B Alpha-cyanoacrylate oxyethyl oxypropyl end-capped cross MDQ silicon resin, and preparation and application thereof 杭州师范大学 2023-06-23 CN claimed
CN-114573815-A Quick-crosslinking-curing MQ-type silicon resin and preparation method and application thereof 杭州师范大学 2022-06-03 CN claimed
CN-114409903-A Alpha-cyanoacrylate-acetoxy-ethylene-oxypropyl-terminated cross MDQ silicon resin and preparation and application thereof 杭州师范大学 2022-04-29 CN claimed
CN-114573815-B Quick-crosslinking-curing MQ type silicon resin and preparation method and application thereof 杭州师范大学 2023-07-25 CN disclosed
CN-114409903-B Alpha-cyanoacrylate oxyethyl oxypropyl end-capped cross MDQ silicon resin, and preparation and application thereof 杭州师范大学 2023-06-23 CN disclosed
CN-114573815-A Quick-crosslinking-curing MQ-type silicon resin and preparation method and application thereof 杭州师范大学 2022-06-03 CN disclosed
CN-114409903-A Alpha-cyanoacrylate-acetoxy-ethylene-oxypropyl-terminated cross MDQ silicon resin and preparation and application thereof 杭州师范大学 2022-04-29 CN disclosed
EP-1550664-B1 SILICON COMPOUND JNC CORP (JP) 2012-06-27 EP disclosed
US-7632904-B2 High refractive-index, hydrophilic, arylsiloxy-containing monomers and polymers, and ophthalmic devices comprising such polymers BAUSCH & LOMB INCORPORATED (US) 2009-12-15 US disclosed
US-7399819-B2 Silicon compound CHISSO CORPORATION (JP) 2008-07-15 US disclosed
US-7297160-B2 High refractive-index, hydrophilic, arylsiloxy-containing macromonomers and polymers, and ophthalmic devices comprising such polymers BAUSCH & LOMB INCORPORATED (US) 2007-11-20 US disclosed
EP-0646616-B1 Organopolysiloxanes having bifunctional siloxane end groups WACKER CHEMIE GMBH (DE) 1997-03-05 EP disclosed
US-5527935-A Organopolysiloxanes having bifunctional terminal siloxane units WACKER-CHEMIE GMBH (DE) 1996-06-18 US disclosed
EP-0646616-A1 Organopolysiloxanes having bifunctional siloxane end groups Wacker-Chemie GmbH (DE) 1995-04-05 EP disclosed
US-5047491-A Molding materials; waterproofing, oil repellents, antifouling agents CHISSO CORPORATION (JP) 1991-09-10 US disclosed
EP-0355497-A2 Polyorganosiloxane compounds Chisso Corporation (JP) 1990-02-28 EP disclosed