Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8747334 | 1.00 | TLR4 (0.32) | TLR4 | |
| SCHEMBL12104221 | 0.72 | — | — | |
| SCHEMBL7775412 | 0.63 | — | — | |
| SCHEMBL21648090 | 0.63 | POLB (0.33) | — | |
| SCHEMBL28544847 | 0.61 | MCL1 (0.42) | TLR4 | |
| SCHEMBL14470654 | 0.61 | PARP1 (0.35) | — | |
| SCHEMBL21648217 | 0.61 | — | — | |
| SCHEMBL21648208 | 0.61 | — | — | |
| SCHEMBL8556521 | 0.60 | CA1 (0.39) | — | |
| SCHEMBL1132078 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548186-B1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES | BEECHAM GROUP PLC (GB) | 1997-03-05 | — | — | EP | disclosed |
| EP-0548186-A1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES. | BEECHAM GROUP PLC (GB) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992004353-A1 | CEPHALOSPORIN DERIVATIVES AND THEIR HOMOLOGUES | BEECHAM GROUP PLC (GB) | 1992-03-19 | — | — | WO | disclosed |