Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9464860 | 1.00 | CA1 (0.39) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL4951980 | 0.82 | CA1 (0.40) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL17822545 | 0.80 | CA1 (0.43) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL19919867 | 0.80 | CA1 (0.43) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL19388490 | 0.80 | CA1 (0.43) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL19388489 | 0.77 | CYP1A2 (0.42) | CA1CA9CYP1A2PRKCA | |
| SCHEMBL4695404 | 0.77 | — | — | |
| SCHEMBL17822536 | 0.77 | — | — | |
| SCHEMBL9201455 | 0.77 | — | — | |
| SCHEMBL5004697 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395219-B1 | Cephalosporins and their homologues, process for their preparation and pharmaceutical compositions | PFIZER (US) | 1998-09-30 | — | — | EP | disclosed |