Carbon Monoxide

Carbon Monoxide

SCHEMBL8747366

O=C(O)c1ccccc1Cl.[C]=O.[Ru].c1ccc(P(c2ccccc2)c2ccccc2)cc1.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.68

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.68
TSHR P16473 2/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
ERCC5 P28715 1/20 0.46
FEN1 P39748 1/20 0.46
ALOX15 P16050 1/20 0.45
POLB P06746 2/20 0.44
CYP3A4 P08684 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
PBRM1 Q86U86 1/20 0.41
HPGD P15428 3/20 0.41
TP53 P04637 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
HTT P42858 1/20 0.41
MEN1 O00255 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6917482 0.84 ALDH1A1 (0.95) ALDH1A1TSHRCES2CES1ERCC5
SCHEMBL29518925 0.82 ALDH1A1 (1.00) ALDH1A1TSHRCES2CES1ERCC5
SCHEMBL29004189 0.82 ALDH1A1 (1.00) ALDH1A1TSHRCES2CES1ERCC5
SCHEMBL29369803 0.82 ALDH1A1 (1.00) ALDH1A1TSHRCES2CES1ERCC5
SCHEMBL8482425 0.82 ALDH1A1 (1.00) ALDH1A1TSHRCES2CES1ERCC5
SCHEMBL367 0.82 ALDH1A1 (1.00) ALDH1A1TSHRCES2CES1ERCC5
Fluoride SCHEMBL6444932 0.80 ALDH1A1 (0.95) ALDH1A1TSHRCES2CES1ERCC5
SCHEMBL6915337 0.80 ALDH1A1 (0.95) ALDH1A1TSHRCES2CES1ERCC5
SCHEMBL6915594 0.80 ALDH1A1 (0.95) ALDH1A1TSHRCES2CES1ERCC5
SCHEMBL8612015 0.80 ALDH1A1 (0.95) ALDH1A1TSHRCES2CES1ERCC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0588097-B1 Nitrile rubber hydrogenation BAYER RUBBER INC (CA) 1997-01-15 EP claimed
EP-0588096-B1 Hydrogenation of nitrile rubber BAYER RUBBER INC (CA) 1996-01-17 EP claimed
EP-0588096-A1 Hydrogenation of nitrile rubber BAYER RUBBER INC. (CA) 1994-03-23 EP claimed
EP-0588097-A1 Nitrile rubber hydrogenation BAYER RUBBER INC. (CA) 1994-03-23 EP claimed
US-5210151-A Ruthenium catalyst, molecular weight increase in minimized POLYSAR RUBBER CORPORATION (CA) 1993-05-11 US claimed
US-5208296-A Ruthenium Phosphine Catalyst POLYSAR RUBBER CORPORATION (CA) 1993-05-04 US claimed