SCHEMBL8747635

SCHEMBL8747635

O=S(=O)(CCSc1nnnn1-c1ccccc1)CC(O)CS(=O)(=O)CCSc1nnnn1-c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.57
ALDH1A1 P00352 12/20 0.55
POLB P06746 3/20 0.55
MEN1 O00255 1/20 0.55
MAPT P10636 1/20 0.55
KMT2A Q03164 1/20 0.55
SMN1; SMN2 Q16637 4/20 0.52
TSHR P16473 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
NPC1 O15118 1/20 0.52
NFKB1 P19838 1/20 0.52
RAB9A P51151 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
LMNA P02545 3/20 0.51
HPGD P15428 2/20 0.51
PKM P14618 1/20 0.51
TP53 P04637 1/20 0.51
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769246 0.81 HSD17B10 (0.58) HSD17B10ALDH1A1POLBMEN1MAPT
SCHEMBL10994113 0.81 HSD17B10 (0.70) HSD17B10ALDH1A1POLBMEN1MAPT
SCHEMBL10995696 0.80 HSD17B10 (0.62) HSD17B10ALDH1A1POLBMEN1MAPT
SCHEMBL10998268 0.78 HSD17B10 (0.62) HSD17B10ALDH1A1POLBMEN1MAPT
SCHEMBL15501201 0.78 ALDH1A1 (0.60) HSD17B10ALDH1A1POLBMEN1MAPT
SCHEMBL10970208 0.75 ALDH1A1 (0.71) HSD17B10ALDH1A1POLBMEN1MAPT
SCHEMBL10973042 0.75 ALDH1A1 (0.71) HSD17B10ALDH1A1POLBMEN1MAPT
SCHEMBL8827915 0.75 POLB (0.74) HSD17B10ALDH1A1POLBMEN1MAPT
SCHEMBL10996145 0.74 HSD17B10 (0.55) HSD17B10ALDH1A1POLBMEN1MAPT
SCHEMBL2377572 0.73 POLB (0.67) ALDH1A1POLBMEN1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0464609-B1 Photographic element FUJI PHOTO FILM CO LTD (JP) 1997-03-12 EP disclosed
US-5212051-A Acrylic copolymers containing carboxy, sulfo or phosphate groups modified by cellulose ethers or esters; barriers to diffusion for diffusion transfer films; flexible coatings FUJI PHOTO FILM CO., LTD. (JP) 1993-05-18 US disclosed
EP-0464609-A2 Photographic element FUJI PHOTO FILM CO., LTD. (JP) 1992-01-08 EP disclosed
US-4996137-A Developing exposed material containing emulsion layer with hexagonal tabular silver bromide core/shell grains FUJI PHOTO FILM CO., LTD. (JP) 1991-02-26 US disclosed
US-H817-H Photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-09-04 US disclosed
US-4859564-A Color diffusion transfer photographic element with reducing sugar FUJI PHOTO FILM CO., LTD. (JP) 1989-08-22 US disclosed