SCHEMBL8747642

SCHEMBL8747642

Cc1cc(CC(=O)Cl)cc(C(C)(C)C)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.50
CYP2C9 P11712 3/20 0.50
CYP2C19 P33261 3/20 0.50
ALDH1A1 P00352 5/20 0.45
KMT2A Q03164 5/20 0.45
MEN1 O00255 4/20 0.45
TSHR P16473 3/20 0.45
HIF1A Q16665 3/20 0.45
MAPK1 P28482 3/20 0.45
LMNA P02545 3/20 0.45
CYP3A4 P08684 2/20 0.45
BLM P54132 2/20 0.45
ATM Q13315 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
TP53 P04637 2/20 0.45
GMNN O75496 1/20 0.45
GABBR2 O75899 1/20 0.45
ALOX15 P16050 1/20 0.45
NFKB1 P19838 1/20 0.45
PMP22 Q01453 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6965645 0.90 ALDH1A1 (0.55) CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A
SCHEMBL283522 0.85 CYP1A2 (0.52) CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A
SCHEMBL29609501 0.84 GAA (0.54) CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A
SCHEMBL28232474 0.84 GAA (0.54) CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A
SCHEMBL11519192 0.84 HMGB1 (0.46) CYP1A2CYP2C9ALDH1A1KMT2AMEN1
SCHEMBL14791819 0.83 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A
SCHEMBL4815659 0.83 CYP1A2 (0.46) CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A
SCHEMBL9556746 0.82 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A
SCHEMBL29104736 0.82 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A
SCHEMBL8994600 0.82 CYP1A2 (0.49) CYP1A2CYP2C9CYP2C19ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed