SCHEMBL8747669

SCHEMBL8747669

NCc1cc(C2CCCCC2)c(O)c(C2CCCCC2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NUDT1 P36639 1/20 0.54
BACE1 P56817 1/20 0.54
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 1/20 0.46
HSP90AA1 P07900 1/20 0.36
HTR2A P28223 2/20 0.35
LOX P28300 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
TDO2 P48775 1/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 2/20 0.34
HSD17B10 Q99714 1/20 0.34
TSHR P16473 1/20 0.34
FEN1 P39748 1/20 0.33
PTPN5 P54829 2/20 0.33
PTPN2 P17706 1/20 0.33
CSNK2A1 P68400 1/20 0.33
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27861753 0.88 NUDT1 (0.48) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL28285412 0.88 NUDT1 (0.48) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL11614576 0.84 NUDT1 (0.49) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL11625563 0.82 NUDT1 (0.46) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL11672043 0.81 NUDT1 (0.46) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL9182472 0.81 NUDT1 (0.50) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL9180445 0.79 NUDT1 (0.49) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL9178169 0.79 NUDT1 (0.49) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL9184053 0.79 NUDT1 (0.49) NUDT1BACE1KDM4EMEN1MAPT
SCHEMBL9183822 0.79 NUDT1 (0.49) NUDT1BACE1KDM4EMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0459950-B1 Stabilisation of dyes on polyamide fibres CIBA GEIGY AG (CH) 1997-03-12 EP disclosed
EP-0438381-B1 Stabilization of dyes on polyamide fibres CIBA GEIGY AG (CH) 1995-04-05 EP disclosed
US-5356443-A Treating fiber before fixation step with sterically hindered phenol and sulfo containing compound CIBA-GEIGY CORPORATION (US) 1994-10-18 US disclosed
US-5181935-A THERMAL AND PHOTOCHEMICAL STABILIZATION OF DYEINGS ON POLYAMIDE FIBERS:STERICALLY HINDERED PHENOL AND ULTRA-VIOLET ABSORBER CIBA-GEIGY CORPORATION (US) 1993-01-26 US disclosed
US-5096456-A Exhaust or continuous dyeing; carpets automotive fabrics, brassiers CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0459950-A1 Stabilisation of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-12-04 EP disclosed
EP-0438381-A1 Stabilization of dyes on polyamide fibres CIBA-GEIGY AG (CH) 1991-07-24 EP disclosed