Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | DGKA | P23743 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10321212 | 1.00 | GPR84 (0.44) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL10325174 | 1.00 | GPR84 (0.44) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL10322566 | 1.00 | GPR84 (0.44) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL8178445 | 1.00 | GPR84 (0.44) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL8176796 | 1.00 | GPR84 (0.44) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL8178199 | 1.00 | GPR84 (0.44) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL9894019 | 0.98 | TSHR (0.41) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL813444 | 0.91 | — | — | |
| Ethylene Glycol SCHEMBL21801572 | 0.91 | TSHR (0.42) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL491650 | 0.91 | TSHR (0.50) | TSHRLMNAALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520281-B1 | Optical element for generating short wave laser light | HOFFMANN LA ROCHE (CH) | 1997-03-12 | — | — | EP | disclosed |
| EP-0520281-A2 | Optical element for generating short wave laser light | F. HOFFMANN-LA ROCHE AG (CH) | 1992-12-30 | — | — | EP | disclosed |