SCHEMBL8747702

SCHEMBL8747702

CONC(=O)N(C)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.49
SLC6A3 Q01959 3/20 0.42
SLC6A2 P23975 1/20 0.42
HDAC3 O15379 1/20 0.42
HDAC1 Q13547 1/20 0.42
HDAC2 Q92769 1/20 0.42
HDAC6 Q9UBN7 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MCHR1 Q99705 1/20 0.41
TSHR P16473 1/20 0.41
GPBAR1 Q8TDU6 1/20 0.39
LMNA P02545 1/20 0.39
ALDH1A1 P00352 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10748756 0.86 MEN1 (0.51) APEX1HDAC3HDAC1HDAC2HDAC6
SCHEMBL7052343 0.81 APEX1 (0.49) APEX1HDAC3HDAC1HDAC2HDAC6
SCHEMBL28656071 0.81 TSHR (0.49) SMN1; SMN2TSHRGPBAR1LMNAALDH1A1
SCHEMBL30047589 0.81 APEX1 (0.49) APEX1HDAC3HDAC1HDAC2HDAC6
SCHEMBL11398672 0.78 APEX1 (0.43) APEX1SLC6A3SLC6A2HDAC3HDAC1
SCHEMBL28663695 0.76 RAB9A (0.47) SMN1; SMN2TSHRALDH1A1KDM4EGAA
SCHEMBL2095708 0.75 APEX1 (0.44) APEX1HDAC3HDAC1HDAC2HDAC6
SCHEMBL10865877 0.75 FSCN1 (0.50) APEX1HDAC3HDAC1HDAC2HDAC6
SCHEMBL1324846 0.75 TSHR (0.45) APEX1HDAC3HDAC1HDAC2HDAC6
SCHEMBL11722664 0.75 APEX1 (0.44) APEX1HDAC3HDAC1HDAC2HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0471204-B1 Antifouling paint compositions NIPPON PAINT CO LTD (JP) 1997-03-12 EP disclosed